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[1] [2] Each item on the scale is scored independently, and the summation of the scores yields an aggregate value that correlates to the severity of alcohol withdrawal, with ranges of scores designed to prompt specific management decisions such as the administration of benzodiazepines. The maximum score is 67; Mild alcohol withdrawal is defined ...
The withdrawal process is typically followed using the Clinical Institute Withdrawal Assessment for Alcohol scale (CIWA-Ar). [3] The typical treatment of alcohol withdrawal is with benzodiazepines such as chlordiazepoxide or diazepam. [2] Often the amounts given are based on a person's symptoms. [2] Thiamine is recommended routinely. [2]
Dosing of the benzodiazepines can be guided by the CIWA scale. [10] The scale is available online. [11] Regarding the choice of benzodiazepine: Chlordiazepoxide (Librium) is the benzodiazepine of choice in uncomplicated alcohol withdrawal due to its long half-life. [12]
Chlordiazepoxide, sold under the brand name Librium among others, is a sedative and hypnotic medication of the benzodiazepine class. It is used to treat anxiety, insomnia and symptoms of withdrawal from alcohol, benzodiazepines, and other drugs. Chlordiazepoxide has a medium to long half-life, while its active metabolite has a very
"Time to peak" refers to when maximum levels of the drug in the blood occur after a given dose. Benzodiazepines generally share the same pharmacological properties, such as anxiolytic, sedative, hypnotic, skeletal muscle relaxant, amnesic, and anticonvulsant effects. Variation in potency of certain effects may exist amongst individual ...
By Akash Sriram (Reuters) - Self-driving technology company Waabi said on Tuesday it has partnered with truckmaker Volvo's driverless systems unit to develop and deploy big rigs that drive themselves.
(Reuters) -Shopify posted its best quarterly revenue growth in three years on Tuesday, as healthy consumer spending and the e-commerce company's efforts to load its platform with AI features for ...
The molecular structure of chlordiazepoxide, the first benzodiazepine, marketed by Hoffmann–La Roche beginning in 1960 and branded as Librium. The first benzodiazepine, chlordiazepoxide (Librium), was synthesized in 1955 by Leo Sternbach while working at Hoffmann–La Roche on the development of tranquilizers. The pharmacological properties ...
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