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This single cell shows the process of the central dogma of molecular biology, which are all steps researchers are interested to quantify (DNA, RNA, and Protein).. In cell biology, single-cell analysis and subcellular analysis [1] refer to the study of genomics, transcriptomics, proteomics, metabolomics, and cell–cell interactions at the level of an individual cell, as opposed to more ...
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Analysis of single-cell sequencing presents many challenges, such as determining the best way to normalize the data. [8] Due to a new level of complications that arise from sequencing of both proteins and transcripts at a single-cell level, the developers of CITE-Seq and their collaborators are maintaining several tools to help with data analysis.
Single-cell DNA genome sequencing involves isolating a single cell, amplifying the whole genome or region of interest, constructing sequencing libraries, and then applying next-generation DNA sequencing (for example Illumina, Ion Torrent). Single-cell DNA sequencing has been widely applied in mammalian systems to study normal physiology and ...
Anduril is an open source component-based workflow framework for scientific data analysis [2] developed at the Systems Biology Laboratory, University of Helsinki. Anduril is designed to enable systematic, flexible and efficient data analysis, particularly in the field of high-throughput experiments in biomedical research.
Nextflow is a scientific workflow system predominantly used for bioinformatic data analysis. It establishes standards for programmatically creating a series of dependent computational steps and facilitates their execution on various local and cloud resources.
CLC bio, a bioinformatics analysis and workflow management platform from QIAGEN Digital Insights. Clone Manager from Sci-Ed. Cuneiform: A functional workflow language for large-scale data analysis [7] Discovery Net: one of the earliest examples of a scientific workflow system, later commercialized as InforSense which was then acquired by IDBS.
The warehouse (datastore, data store, file, database) is used to store data for later use. The symbol of the store is two horizontal lines, the other way of view is shown in the DFD Notation. The name of the warehouse is a plural noun (e.g. orders)—it derives from the input and output streams of the warehouse.