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2. Methotrexate - Wikipedia

   en.wikipedia.org/wiki/Methotrexate

   Methotrexate was originally developed and continues to be used for chemotherapy, either alone or in combination with other agents.It is effective for the treatment of several cancers, including solid tumours of breast, head and neck, lung, bladder, as well as acute lymphocytic leukemias, non-Hodgkin's lymphoma, osteosarcoma, and choriocarcinoma and other trophoblastic neoplasms.

3. Immunosuppressive drug - Wikipedia

   en.wikipedia.org/wiki/Immunosuppressive_drug

   Methotrexate is a folic acid analogue. It binds dihydrofolate reductase and prevents synthesis of tetrahydrofolate . It is used in the treatment of autoimmune diseases (for example rheumatoid arthritis or Behcet's Disease) and in transplantations.

4. Antiarthritics - Wikipedia

   en.wikipedia.org/wiki/Antiarthritics

   Methotrexate is commonly associated with dose-related toxic effects involving the bone marrow and gastrointestinal tract. [12] Folic acid may be given weekly to help diminish the frequency of side-effects. [12] Methotrexate is also associated with acute and chronic liver damage. Other adverse effects include: [12] Life-threatening Interstitial ...

5. What Is Methotrexate, Exactly, and How Does It Play Into ...

   www.aol.com/lifestyle/methotrexate-exactly-does...

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6. Rheumatoid arthritis - Wikipedia

   en.wikipedia.org/wiki/Rheumatoid_arthritis

   The most commonly used agent is methotrexate with other frequently used agents including sulfasalazine and leflunomide. [8] Leflunomide is effective when used from 6–12 months, with similar effectiveness to methotrexate when used for 2 years. [119] Sulfasalazine also appears to be most effective in the short-term treatment of rheumatoid ...

7. Central nervous system prophylaxis - Wikipedia

   en.wikipedia.org/wiki/Central_nervous_system...

   The most popular type of CNS prophylactic drug is methotrexate (MTX), an antimetabolite and immunomodulator known to fight lymphoma by interfering with cell growth and division. Contrary to systemic treatments, delivery of MTX to its target site is relatively difficult, due to the drug-expelling properties of the blood-brain barrier via P ...

8. Are Diabetes Drugs Really Safe (& Reliable) for Weight Loss?

   www.aol.com/diabetes-drugs-really-safe-reliable...

   Are Diabetes Weight Loss Drugs Safe? Generally speaking, GLP-1s, GIP/GLP-1s, and metformin are considered safe and effective when used as prescribed. That said, no medication is without side effects.

9. Bill Murray Defends ‘SNL’ Against Viewers Slamming the Show ...

   www.aol.com/bill-murray-defends-snl-against...

   Bill Murray appeared on Travis and Jason Kelce’s “New Heights” podcast (via The Daily Beast) and defended the current cast of “Saturday Night Live” from critics who say the show has ...