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Varenicline, sold under the brand names Chantix and Champix among others, is a medication used for smoking cessation [5] [7] and for the treatment of dry eye syndrome. [ 6 ] [ 8 ] It is a nicotinic acetylcholine receptor partial agonist .
Chantix is a prescription drug that can help people quit smoking tobacco. Medicare’s prescription drug plans include coverage for certain smoking cessation drugs, including Chantix.
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product. The other sections are as follows:
Giving up smoking is associated with an average weight gain of 4–5 kilograms (8.8–11.0 lb) after 12 months, most of which occurs within the first three months of quitting. [199] The possible causes of the weight gain include: Smoking over-expresses the gene AZGP1 which stimulates lipolysis, so smoking cessation may decrease lipolysis. [200]
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The success rate for Chantix appears to be about 44% after three months, far above other products on the market. The one year success rate is about 22%, still far higher than other methods of quitting. The reason for this drop is because Chantix is a tool, not a magic pill, and nicotine is an insidious addiction.
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Nicotine replacement therapy is as effective as medications, such as bupropion, in helping people quit smoking for at least six months. [16] All forms of nicotine replacement therapy, including nicotine gum, patches, nasal spray, inhalers, and lozenges, have similar success rates in terms of helping people stop smoking.
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