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Chronic periodontitis is initiated by Gram-negative tooth-associated microbial biofilms that elicit a host response, which results in bone and soft tissue destruction. In response to endotoxin derived from periodontal pathogens, several osteoclast-related mediators target the destruction of alveolar bone and supporting connective tissue such as the periodontal ligament.
Periapical periodontitis; Other names: Apical periodontitis, periradicular periodontitis: Periapical dental radiograph showing chronic periapical periodontitis on the root of the left maxillary second premolar. Note large restoration present in the tooth, which will have undergone pulpal necrosis at some point before the development of this lesion.
Aggressive periodontitis is distinguished from the chronic form mainly by the faster rate of progression. Loss of attachment may progress despite good oral hygiene and in the absence of risk factors such as smoking. Aggressive periodontitis may occur in younger persons and there may a genetic aspect, with the trait sometimes running in families ...
Gum disease is the most common oral disease, with studies estimating that up to 80% of Americans have dealt with periodontal disease at some point during their lives. The prevalence of gum disease ...
Chronic periodontitis affects about 750 million people or about 10.8% of the world population as of 2010. [ 86 ] Like other conditions intimately related to access to hygiene and basic medical monitoring and care, periodontitis tends to be more common in economically disadvantaged populations or regions.
[1] [2] At least 16 systemic diseases have been linked to periodontitis. These systemic diseases are associated with periodontal disease because they generally contribute to either a decreased host resistance to infections or dysfunction in the connective tissue of the gums , increasing patient susceptibility to inflammation-induced destruction.
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