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Virilization is a medical term commonly used in three medical and biology of sex contexts: prenatal biological sexual differentiation, the postnatal changes of typical chromosomal male (46, XY) puberty, and excessive androgen effects in typical chromosomal females (46, XX).
It was described as a disorder of anxiety or depression related to an uncertainty about one's gender identity or sexual orientation. [2] In 2014, it was determined that there was no justification for the existence of this mental disorder category, and the diagnosis was not included in the ICD-11 , which went into effect in January 2022.
Aromatase deficiency is a rare condition characterized by extremely low levels or complete absence of the enzyme aromatase activity in the body. [2] It is an autosomal recessive disease resulting from various mutations of gene CYP19 (P450arom) which can lead to ambiguous genitalia and delayed puberty in females, continued linear growth into adulthood and osteoporosis in males and virilization ...
Complete androgen insensitivity syndrome causes a genetic male to have a vagina (often incompletely developed, nearly always blind-ending), breasts, and a clitoris; people with this form are raised as females. [25] Aphallia – a rare condition where a XY male is born without a penis. As of 2017, only 100 cases have been reported in literature ...
During puberty, a male's erect penis becomes capable of ejaculating semen and impregnating a female. [26] [27] A male's first ejaculation is an important milestone in his development. [28] On average, a male's first ejaculation occurs at age 13. [29] Ejaculation sometimes occurs during sleep; this phenomenon is known as a nocturnal emission. [25]
Pseudohermaphroditism is an outdated [1] term for when an individual's gonads were mismatched with their internal reproductive system and/or external genitalia. The term was contrasted with "true hermaphroditism" (now known as ovotesticular syndrome), a condition describing an individual with both female and male reproductive gonadal tissues.
It is not uncommon for patients to be diagnosed later in life due to short stature or delayed puberty, or a combination of both. [ 8 ] 45,X/46,XY mosaicism can be detected prenatally through amniocentesis however, it was determined that the proportion of 45,X cells in the amniotic fluid cannot predict any phenotypic outcomes, often making ...
The embryo and subsequent early fetus appear to be sexually indifferent, looking neither like a male or a female. Over the next several weeks, hormones are produced that cause undifferentiated tissue to transform into either male or female reproductive organs. This process is called sexual differentiation.