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Acute blockage (embolism) of a blood vessel by a thrombus that has detached from its place of formation (on the wall of a vessel) and entered the circulating blood. As a result of this blockage, blood flow in the vessel stops—a condition called thromboembolism. [1] Thromboembolism is a condition in which a blood clot breaks off from its ...
Thrombosis prophylaxis is effective in preventing the formation of blood clots, their lodging in the veins, and their developing into thromboemboli that can travel through the circulatory system to cause blockage and subsequent tissue death in other organs. [1] Clarence Crafoord is credited with the first use of thrombosis prophylaxis in the 1930s.
Nevertheless, non-ischemic venous thrombosis may still be problematic, due to the swelling caused by blockage to venous drainage. In deep vein thrombosis this manifests as pain, redness, and swelling; in retinal vein occlusion this may result in macular oedema and visual acuity impairment, which if severe enough can lead to blindness.
If having thrombophlebitis or thrombosis; pain when using the access is another complication. Peripheral venous access is least prone to thrombosis, followed by midline catheters and the centrally placed catheters. Central venous access is the most common reason for venous thrombosis in children. [citation needed]
Venalex is used to treat chronic functional or structural venous insufficiency of the lower limbs. [2] No results of clinical trials have been published. [citation needed] Venalex is not currently approved by the FDA. [3]
When using central venous access, the subclavian (or axillary) vein is preferred due to its ease of access and lowest infectious complications compared to the jugular and femoral vein insertions. [6] Catheter complications include pneumothorax, accidental arterial puncture, and catheter-related sepsis. The complication rate at the time of ...
Possible complications of arterial embolism depend on the site of the obstruction: In the heart it can cause myocardial infarction [2] In the brain, it can cause a transient ischemic attack (TIA), [2] and, in prolonged blood obstruction, stroke. [2] Blockage of arteries that supply arms or legs may result in necrosis and gangrene [1]
If the impaired vein function causes significant symptoms, such as swelling and ulcer formation, it is referred to as chronic venous disease. [3] It is sometimes called chronic peripheral venous insufficiency and should not be confused with post-thrombotic syndrome in which the deep veins have been damaged by previous deep vein thrombosis .
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