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  2. ACTH stimulation test - Wikipedia

    en.wikipedia.org/wiki/ACTH_stimulation_test

    The ACTH test (also called the cosyntropin, tetracosactide, or Synacthen test) is a medical test usually requested and interpreted by endocrinologists to assess the functioning of the adrenal glands' stress response by measuring the adrenal response to adrenocorticotropic hormone (ACTH; corticotropin) or another corticotropic agent such as tetracosactide (cosyntropin, tetracosactrin; Synacthen ...

  3. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...

  4. Adrenocorticotropic hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocorticotropic_hormone

    ACTH stimulates secretion of glucocorticoid steroid hormones from adrenal cortex cells, especially in the zona fasciculata of the adrenal glands. ACTH acts by binding to cell surface ACTH receptors, which are located primarily on adrenocortical cells of the adrenal cortex. The ACTH receptor is a seven-membrane-spanning G protein-coupled ...

  5. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

    en.wikipedia.org/wiki/Congenital_adrenal...

    ACTH stimulates uptake of cholesterol and synthesis of pregnenolone. Steroid precursors up to and including progesterone, 17α-hydroxypregnenolone, and especially 17OHP accumulate in the adrenal cortex and in circulating blood. Blood levels of 17OHP can reach 10-1000 times the normal concentration. [163]

  6. Adrenocortical hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocortical_hormone

    ACTH then travels to the adrenal glands and induces the release of cortisol into the bloodstream. [7] In Cushing's syndrome, this process occurs in excess. Some symptoms of an individual with Cushing's syndrome include low tissue protein levels, due to muscle and bone atrophy, and high blood glucose levels. Sodium levels also see an increase ...

  7. Adrenocorticotropic hormone deficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenocorticotropic...

    Low blood sugar and hyponatremia are possible; however, blood potassium levels typically remain normal because affected patients are deficient in glucocorticoids rather than mineralocorticoids because of their intact renin-angiotensin-aldosterone system. ACTH may be undetectable in blood tests, and cortisol is abnormally low. [1]

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  9. Corticotropic cell - Wikipedia

    en.wikipedia.org/wiki/Corticotropic_cell

    The release of ACTH from the corticotropic cells is controlled by CRH, which is formed in the cell bodies of parvocellular neurosecretory cells within the paraventricular nucleus of the hypothalamus and passes to the corticotropes in the anterior pituitary via the hypophyseal portal system.