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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity. [4] [5]
Scientists from the University of Exeter Medical School have found that people missing a specific blood group due to a genetic variant may be genetically predisposed to having obesity or overweight.
Research into genetic factors and potential treatments is still underway, but Scherer said the current best approach to medical treatment of obesity is GLP-1 medications.
Fat mass and obesity-associated protein, also known as alpha-ketoglutarate-dependent dioxygenase FTO, is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. As one homolog in the AlkB family proteins, it is the first messenger RNA (mRNA) demethylase that has been identified. [ 5 ]
Symptoms of Obesity. ... Certain genetic conditions can also cause obesity. For example, Prader-Willi syndrome is an inherited disorder that leads to, among other complications, intellectual ...
In medicine, genetic susceptibility to a disease refers to a genetic predisposition to a health problem, [1] which may eventually be triggered by particular environmental or lifestyle factors, such as tobacco smoking or diet. Genetic testing is able to identify individuals who are genetically predisposed to certain diseases.
Some people’s genetics predispose them to obesity. But nature is not destiny. Here are five tips for losing weight.
Prentice et al [5] predicted that the emerging molecular genetics field would ultimately provide a way to test between the adaptive 'thrifty gene' idea and the non-adaptive 'drifty gene' idea because it would be possible to find signatures of positive selection in the human genome, at genes that are linked to both obesity and type 2 diabetes ...