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MRI has the advantages of having very high spatial resolution and is very adept at morphological imaging and functional imaging. MRI does have several disadvantages though. First, MRI has a sensitivity of around 10 −3 mol/L to 10 −5 mol/L, which, compared to other types of imaging, can be very limiting.
Real-time magnetic resonance imaging (RT-MRI) refers to the continuous monitoring of moving objects in real time. Traditionally, real-time MRI was possible only with low image quality or low temporal resolution. An iterative reconstruction algorithm removed limitations.
Resolution: Medical MRI resolution is typically about 1 mm; the desired resolution of MRM is 100 μm or smaller to 10 μm, comparable with histology. Specimen size: Medical MRI machines are designed so that a patient may fit inside. MRM chambers are usually small, typically less than 1 cm 3 for the imaging of rats, mice and rodents. BrukerBio ...
Modern 3 Tesla clinical MRI scanner.. Magnetic resonance imaging (MRI) is a medical imaging technique mostly used in radiology and nuclear medicine in order to investigate the anatomy and physiology of the body, and to detect pathologies including tumors, inflammation, neurological conditions such as stroke, disorders of muscles and joints, and abnormalities in the heart and blood vessels ...
The first MR images of a human brain were obtained in 1978 by two groups of researchers at EMI Laboratories led by Ian Robert Young and Hugh Clow. [1] In 1986, Charles L. Dumoulin and Howard R. Hart at General Electric developed MR angiography, [2] and Denis Le Bihan obtained the first images and later patented diffusion MRI. [3]
In general, fMRI studies acquire both many functional images with fMRI and a structural image with MRI. The structural image is usually of a higher resolution and depends on a different signal, the T1 magnetic field decay after excitation. To demarcate regions of interest in the functional image, one needs to align it with the structural one.
Diffusion imaging is an MRI method that produces in vivo magnetic resonance images of biological tissues sensitized with the local characteristics of molecular diffusion, generally water (but other moieties can also be investigated using MR spectroscopic approaches). [15] MRI can be made sensitive to the motion of molecules.
Most recently, highly undersampled radial FLASH MRI acquisitions have been combined with an iterative image reconstruction by regularized nonlinear inversion to achieve real-time MRI at a temporal resolution of 20 to 30 milliseconds for images with a spatial resolution of 1.5 to 2.0 millimeters. [4]
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