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  2. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

    www.aol.com/lifestyle/viagra-treats-side-effects...

    Viagra (Sildenafil): Uses, Benefits and Side Effects. ... Since 1998, the Pfizer-created drug sildenafil citrate has been a reliable treatment for the management of ED. But the active ingredient ...

  3. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    Side Effects and Risks of Taking Viagra without ED ... the researchers found more than 10 percent of men having intimacy with men used sildenafil citrate — and that its use is associated with ...

  4. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil is sometimes used to counteract the effects of other substances, often illicit. [33] Some users mix it with methylenedioxymethamphetamine ( MDMA , ecstasy), other stimulants, or opiates in an attempt to compensate for the common side effect of erectile dysfunction, a combination known as " sextasy ", "rockin' and rollin ...

  5. What Is the Safest ED Medication? - AOL

    www.aol.com/lifestyle/safest-ed-medication...

    For example, headache — the most common side effect of most oral ED medication — was reported by 21 percent of men who used sildenafil citrate in clinical trials at a 50mg dosage.

  6. 5 Must-Know Tips Before Taking Sildenafil 100mg - AOL

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    Like other medications, sildenafil citrate comes in several doses, ranging from as little as 25 mg a tablet (20 mg when referring to the generic version of Revatio — a medication for a type of ...

  7. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  8. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Sildenafil did not prove effective for coronary heart disease but an interesting side effect was discovered, a penile erection. That side effect soon became the main field of investigation. [23] The inhibitor is highly selective for the PDE5 family. [22] Sildenafil is a prototype of PDE5 inhibitors that Pfizer launched as Viagra.

  9. How to Take Viagra for Best Results - AOL

    www.aol.com/viagra-best-results-105700318.html

    Viagra side effects may affect your ability to perform, though most are mild and temporary. All (ED) medications work best when you’re maintaining a healthy lifestyle. That’s the 30-thousand ...

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