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2. DU145 - Wikipedia

   en.wikipedia.org/wiki/DU145

   Castration-resistant prostate cancer (CRPC) is prostate cancer that progresses despite extremely low testosterone in the body often due to medical castration. [4] Unlike many other types of prostate cancer, CRPC do not need normal testosterone levels, but they still require regular androgen receptors (AR).

3. Tasquinimod - Wikipedia

   en.wikipedia.org/wiki/Tasquinimod

   Tasquinimod has been mostly studied in prostate cancer, but its mechanism of action suggests that it could be used to treat other cancers. Castration-resistant prostate cancer (CRPC), formerly called hormone-resistant or hormone-refractory prostate cancer, is prostate cancer that grows despite medical or surgical androgen deprivation therapy.

4. Proxalutamide - Wikipedia

   en.wikipedia.org/wiki/Proxalutamide

   Proxalutamide (developmental code name GT-0918) is a nonsteroidal antiandrogen (NSAA) – specifically, a selective high-affinity silent antagonist of the androgen receptor (AR) – which is under development by Suzhou Kintor Pharmaceuticals, inc., a subsidiary of Kintor Pharmaceutical Limited, for the potential treatment of COVID-19, prostate cancer, and breast cancer.

5. List of drugs granted breakthrough therapy designation

   en.wikipedia.org/wiki/List_of_drugs_granted...

   prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant. prostate cancer (mCRPC) Alpelisib: Novartis: PIK3CA-related overgrowth spectrum conditions Mavacamten: Myokardia Inc: class II-III obstructive hypertrophic cardiomyopathy: Trastuzumab deruxtecan: Daiichi Sankyo

6. Prostate cancer - Wikipedia

   en.wikipedia.org/wiki/Prostate_cancer

   Eventually cancer cells can grow resistant to this treatment. This most-advanced stage of the disease, called castration-resistant prostate cancer, is treated with continued hormone therapy alongside the chemotherapy drug docetaxel. Some tumors metastasize (spread) to other areas of the body, particularly the bones and lymph nodes.

7. PC3 - Wikipedia

   en.wikipedia.org/wiki/PC3

   Prostate cancer (PC) is the most common form of non-cutaneous malignant cancer in males, and is the second leading cause of cancer deaths in males. [12] PC3 cells have been utilized to research aggressive and castration-resistant forms of pancreatic cancer.