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Triiodothyronine, also known as T 3, is a thyroid hormone. ... The sensitivity of a tissue to T 3 is modulated through the thyroid receptors. Transportation
This receptor-corepressor-DNA complex can block gene transcription. Triiodothyronine (T 3), which is the active form of thyroxine (T 4), goes on to bind to receptors. The deiodinase catalyzed reaction removes an iodine atom from the 5′ position of the outer aromatic ring of thyroxine's (T 4) structure. [63]
Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4), and then triiodothyronine (T 3) which stimulates the metabolism of almost every tissue in the body. [1]
Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.
Triiodothyronine (T 3, pictured) and thyroxine (T 4) are both forms of thyroid hormone. Specialty: Endocrinology: Symptoms: Irritability, muscle weakness, sleeping problems, fast heartbeat, heat intolerance, diarrhea, enlargement of the thyroid, weight loss [1] Complications: Thyroid storm [2] Usual onset: 20–50 years old [2] Causes
The pituitary gland secretes thyrotropin (TSH; Thyroid Stimulating Hormone) that stimulates the thyroid to secrete thyroxine (T4) and, to a lesser degree, triiodothyronine (T3). The major portion of T3, however, is produced in peripheral organs, e.g. liver, adipose tissue, glia and skeletal muscle by deiodination from circulating T4.
Triiodothyronine binds to the thyroid hormone receptor in the nucleus of cells, where it stimulates the turning on of particular genes and the production of specific proteins. [41] Additionally, the hormone binds to integrin αvβ3 on the cell membrane , thereby stimulating the sodium–hydrogen antiporter and processes such as formation of ...
The Thyrotroph Thyroid Hormone Sensitivity Index (abbreviated TTSI, also referred to as Thyrotroph T4 Resistance Index or TT4RI) is a calculated structure parameter of thyroid homeostasis. It was originally developed to deliver a method for fast screening for resistance to thyroid hormone .
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