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Lymphedema is most frequently a complication of cancer treatment or parasitic infections, but it can also be seen in a number of genetic disorders. Tissues with lymphedema are at high risk of infection because the lymphatic system has been compromised. [3] Though incurable and progressive, a number of treatments may improve symptoms. [2]
Aagenaes syndrome is inherited in an autosomal recessive manner Aagenaes syndrome is a syndrome characterised by congenital hypoplasia of lymph vessels , which causes lymphedema of the legs and recurrent cholestasis in infancy, and slow progress to hepatic cirrhosis and giant cell hepatitis with fibrosis of the portal tracts .
Milroy's disease is also known as primary or hereditary lymphedema type 1A or early onset lymphedema. It is a very rare disease with only about 200 cases reported in the medical literature. Milroy's disease is an autosomal dominant condition caused by a mutation in the FLT4 gene which encodes the vascular endothelial growth factor receptor 3 ...
Primary lymphedema is a form of lymphedema which is not directly attributable to another medical condition. It can be divided into three forms, depending upon age of onset: congenital lymphedema, lymphedema praecox, and lymphedema tarda. [1] Congenital lymphedema presents at birth. Lymphedema praecox presents from ages 1 to 35.
Meige lymphedema, Late-onset lymphedema, Lymphedema hereditary type 2, [1] Meige disease , or Meige lymphedema is a genetic disorder in which lymphedema later develops. [ 2 ] Meige disease is a primary lymphedema that is not caused by another condition; secondary lymphedema is a typical consequence of a mastectomy .
Lymphedema is a buildup of lymph in the interstitial space as a result of an obstruction in the lymphatic system, which can cause edema, inflammation, and fibrosis in the tissues. Lymphedema can be primary, when it occurs alone, or secondary, when it occurs as a result of another disease like filariasis or cancer.
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