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Radiation-induced lumbar plexopathy (RILP) or radiation-induced lumbosacral plexopathy (RILSP) is nerve damage in the pelvis and lower spine area caused by therapeutic radiation treatments. RILP is a rare side effect of external beam radiation therapy [ 1 ] [ 2 ] [ 3 ] and both interstitial and intracavity brachytherapy radiation implants.
Diagnosis of plexopathy relies on proper identification of a pattern in motor and sensory function deficits in the upper or lower extremities. [ 1 ] To rule out confounding conditions such as radiculopathy or myelopathy , an MRI of the cervical or lumbar spine is often obtained.
Cervical radiculopathy has an annual incidence rate of 107.3 per 100,000 for men and 63.5 per 100,000 for women, whereas lumbar radiculopathy has a prevalence of approximately 3-5% of the population. [ 26 ] [ 27 ] According to the AHRQ 's 2010 National Statistics for cervical radiculopathy, the most affected age group is between 45 and 64 years ...
A common form of radiculitis is sciatica – radicular pain that radiates along the sciatic nerve from the lower spine to the lower back, gluteal muscles, back of the upper thigh, calf, and foot as often secondary to nerve root irritation from a spinal disc herniation or from osteophytes in the lumbar region of the spine.
The lumbar (or lower back) region is the area between the lower ribs and gluteal fold which includes five lumbar vertebrae (L1–L5) and the sacrum. In between these vertebrae are fibrocartilaginous discs , which act as cushions, preventing the vertebrae from rubbing together while at the same time protecting the spinal cord .
However, the symptoms vary depending on the severity and cause of the condition. Lighter symptoms include pain or heaviness in the legs, hips, glutes and lower back, post-exercise. [6] [8] Mild to severe symptoms include prolonged constant pain, tiredness and discomfort in the lower half of the body.
Normal lumbar vertebra showing large, round spinal canal. The diagnosis is based on clinical findings. [7] Some patients can have a narrowed canal without symptoms, and do not require therapy. [citation needed] The normal lumbar central canal has a midsagittal diameter (front to back) greater than 13 mm, with an area of 1.45 cm 2. Relative ...
The conus medullaris (or lower termination of the spinal cord) normally terminates at or above the L1-2 disk space (where L1 is the first, or topmost lumbar vertebra). After about 3 months of age, a conus below the L1-2 disk space may indicate a tethered cord and termination below L3-4 is unmistakably tethered.
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