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The removal of fluoroquinolones as a potential treatment left cephalosporins as the only viable antimicrobial option for gonorrhea treatment. Wary of further gonococcal resistance, the CDC's recommendations shifted in 2010 to a dual therapy strategy--cephalosporin with either azithromycin or doxycycline.
Gonorrhoea or gonorrhea, colloquially known as the clap, [7] is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae. [8] Infection may involve the genitals, mouth, or rectum. [9] Gonorrhea is spread through sexual contact with an infected person, [1] or from a mother to a child during birth. [1]
Treatment typically consists of cephalosporin and fluoroquinolone antibiotics. [4] Gonococcemia is typically treated with intravenous or intramuscular cephalosporin antibiotics. [ 5 ] Approximately 10-30% of gonorrheal infections present with a co-infection of chlamydia , so it is common to add a one-time dose of oral azithromycin or ...
The antibiotic, which would be the first new gonorrhea treatment approved in decades, could make it to market by 2025. The World Health Organization estimates that globally there are more than 82 ...
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The CDC data shows that 2023 marks the second straight year of decline in the U.S.: gonorrhea decreased by 9.2% between 2021 and 2022 and 7.7% from 2022 to 2023.
The CDC recommends that sexually active women under the age of 25 and those over 25 at risk should be screened for chlamydia and gonorrhea yearly. Appropriate times for screening are during regular pelvic examinations and preconception evaluations. [ 97 ]
Since August 2012, the third-generation cephalosporin, ceftriaxone, is the only recommended treatment for gonorrhea in the United States (in addition to azithromycin or doxycycline for concurrent Chlamydia treatment). Cefixime is no longer recommended as a first-line treatment due to evidence of decreasing susceptibility. [30] Ceftriaxone ...
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