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2. Dapagliflozin - Wikipedia

   en.wikipedia.org/wiki/Dapagliflozin

   Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment

3. New Phase III Data Showed Dapagliflozin Significantly ... - AOL

   www.aol.com/2013/09/24/new-phase-iii-data-showed...

   New Phase III Data Showed Dapagliflozin Significantly Reduced HbA1c Compared to Placebo at 24 Weeks in Patients with Type 2 Diabetes Inadequately Controlled with the Combination of Metformin Plus ...

4. SGLT2 inhibitor - Wikipedia

   en.wikipedia.org/wiki/SGLT2_inhibitor

   Dapagliflozin is an example of an SGLT-2 inhibitor, it is a competitive, highly selective inhibitor of SGLT. It acts via selective and potent inhibition of SGLT-2, and its activity is based on each patient's underlying blood sugar control and kidney function. The results are decreased kidney reabsorption of glucose, glucosuria effect increases ...

5. AstraZeneca's Dapagliflozin No Longer Authorized For Type 1 ...

   www.aol.com/news/astrazenecas-dapagliflozin-no...

   The SGLT2 inhibitor dapagliflozin has been indicated for the treatment of type 2 diabetes since 2012. ... an adjunct to insulin in patients with type 1 diabetes with a body-mass index (BMI) of 27 ...

6. Discovery and development of gliflozins - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   This includes actions to attenuate tubular hypertrophy and hyperfiltration associated with diabetes and to reduce the tubular toxicity of glucose. Inhibition of SGLT-2 following treatment with dapagliflozin reduces the capacity for tubular glucose reabsorption by approximately 30–50%. [8]

7. What Endocrinologists Want You to Know About Rybelsus and Ozempic

   www.aol.com/endocrinologists-want-know-rybelsus...

   As a type 2 diabetes drug, Rybelsus is a prescription oral tablet that, when used alongside diet and exercise, works to improve blood sugar in adults with type 2 diabetes. According to the drug ...