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  2. AstraZeneca's Imfinzi improves survival in late-stage lung ...

    www.aol.com/news/astrazenecas-imfinzi-shows...

    Imfinzi won approval for use in mid-stage non-small cell lung cancer a year later. In March 2020, the FDA approved Imfinzi to target extensive-stage small-cell lung cancer.

  3. Durvalumab - Wikipedia

    en.wikipedia.org/wiki/Durvalumab

    Durvalumab, [8] sold under the brand name Imfinzi, is an FDA-approved immunotherapy for cancer, developed by Medimmune/AstraZeneca. [9] It is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody that blocks the interaction of programmed cell death ligand 1 ( PD-L1 ) with the PD-1 (CD279).

  4. AstraZeneca's Imfinzi gets FDA priority review for type of ...

    www.aol.com/news/astrazenecas-imfinzi-gets-fda...

    Small cell lung cancer is a highly aggressive form of lung cancer. Imfinzi is a human monoclonal antibody, which works by blocking a tumour's ability to evade and dampen the immune system, while ...

  5. AstraZeneca's Imfinzi Shows Long-Term Benefits in Lung Cancer

    www.aol.com/news/astrazenecas-imfinzi-shows-long...

    AstraZeneca (AZN) presents follow-up data on Imfinzi from late-stage PACIFIC study evaluating it in lung cancer patients. AstraZeneca's Imfinzi Shows Long-Term Benefits in Lung Cancer Skip to main ...

  6. Cancer immunotherapy - Wikipedia

    en.wikipedia.org/wiki/Cancer_immunotherapy

    Cancer immunotherapy ... non-small cell lung cancer, small cell lung cancer, hepatocellular carcinoma, ... Durvalumab (Imfinzi) is a human immunoglobulin G1 kappa ...

  7. PD-1 and PD-L1 inhibitors - Wikipedia

    en.wikipedia.org/wiki/PD-1_and_PD-L1_inhibitors

    It failed phase III clinical trials for gastric cancer. [33] Durvalumab (Imfinzi) is a fully human IgG1 antibody developed by AstraZeneca. Durvalumab is FDA approved for the treatment of urothelial carcinoma and unresectable non-small cell lung cancer after chemoradiation. [34]

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