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  2. Prophase - Wikipedia

    en.wikipedia.org/wiki/Prophase

    Prophase is the first step of cell division in mitosis. As it occurs after G2 of interphase, DNA has been already replicated when prophase begins. [1] Fluorescence microscope image of two mouse cell nuclei in prophase (scale bar is 5 μm).

  3. Mitosis - Wikipedia

    en.wikipedia.org/wiki/Mitosis

    In this stage, chromosomes are long, thin, and thread-like. Each chromosome has two chromatids. The two chromatids are joined at the centromere. Gene transcription ceases during prophase and does not resume until late anaphase to early G 1 phase. [40] [41] [42] The nucleolus also disappears during early prophase. [43]

  4. Cell division - Wikipedia

    en.wikipedia.org/wiki/Cell_division

    The thick lines are chromosomes, and the thin blue lines are fibers pulling on the chromosomes and pushing the ends of the cell apart. The cell cycle in eukaryotes: I = Interphase, M = Mitosis, G 0 = Gap 0, G 1 = Gap 1, G 2 = Gap 2, S = Synthesis, G 3 = Gap 3. Cell division is the process by which a parent cell divides into two daughter cells. [1]

  5. Chromosome segregation - Wikipedia

    en.wikipedia.org/wiki/Chromosome_segregation

    Chromosome segregation is the process in eukaryotes by which two sister chromatids formed as a consequence of DNA replication, or paired homologous chromosomes, separate from each other and migrate to opposite poles of the nucleus. This segregation process occurs during both mitosis and meiosis. Chromosome segregation also occurs in prokaryotes ...

  6. Meiotic recombination checkpoint - Wikipedia

    en.wikipedia.org/wiki/Meiotic_recombination...

    Meiotic sex chromosome inactivation only happens in male, which may partially be the reason why only Spo11 mutant spermatocytes but not oocytes fail to transition from prophase I to metaphase I. [3] [8] However the asynapsis does not happen only within sex chromosomes, and such transcription regulation was suspended until it was further ...

  7. Cell cycle - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle

    The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.

  8. Spindle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Spindle_checkpoint

    Using different types of genetic studies, it has been established that diverse kinds of defects are able to activate the SAC: spindle depolymerization, [8] [9] the presence of dicentric chromosomes (with two centromeres), [10] centromeres segregating in an aberrant way, [11] defects in the spindle pole bodies in S. cerevisiae, [12] defects in ...

  9. Leptotene stage - Wikipedia

    en.wikipedia.org/wiki/Leptotene_stage

    During the leptotene stage, the duplicated chromosomes - each consisting of two sister chromatids - condense from diffuse chromatin into long, thin strands that are more visible within the nucleoplasm (nucleus contents). The chromosomes become visible as thin threadlike structures known as leptonema under a light microscope. [1]: 27 [2]: 353