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  2. Drug resistance - Wikipedia

    en.wikipedia.org/wiki/Drug_resistance

    Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. [1] The term is used in the context of resistance that pathogens or cancers have "acquired", that is, resistance has evolved.

  3. HIV drug resistance - Wikipedia

    en.wikipedia.org/wiki/HIV_drug_resistance

    Drug resistance occurs as bacterial or viral populations evolve to no longer respond to medications that previously worked. In the case of HIV, there have been recognized cases of treatment resistant strains since 1989, with drug resistance being a major contributor to treatment failure. [1]

  4. Antineoplastic resistance - Wikipedia

    en.wikipedia.org/wiki/Antineoplastic_resistance

    Similarly, in drug resistance development, it has been suggested that epigenetic modifications can result in the activation and overexpression of pro-drug resistance genes. [ 12 ] Studies on cancer cell lines have shown that hypomethylation (loss of methylation) of the MDR1 gene promoter caused overexpression and the multidrug resistance.

  5. Drug tolerance - Wikipedia

    en.wikipedia.org/wiki/Drug_tolerance

    drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose; drug withdrawal – symptoms that occur upon cessation of repeated drug use; physical dependence – dependence that involves persistent physical–somatic withdrawal symptoms (e.g., fatigue and delirium tremens)

  6. Antimicrobial resistance - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_resistance

    A person cannot become resistant to antibiotics. Resistance is a property of the microbe, not a person or other organism infected by a microbe. [14] All types of microbes can develop drug resistance. Thus, there are antibiotic, antifungal, antiviral and antiparasitic resistance. [4] [8] Antibiotic resistance is a subset of antimicrobial resistance.

  7. Fentanyl in other drugs: Why do drug dealers mix them ... - AOL

    www.aol.com/fentanyl-other-drugs-why-drug...

    In addition to the added potency, the drug has a “low cost,” which leads drug dealers to mix fentanyl with drugs like “heroin, methamphetamine and cocaine, increasing the likelihood of a ...

  8. Multidrug-resistant tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Multidrug-resistant...

    In general, resistance to one drug within a class means resistance to all drugs within that class, but a notable exception is rifabutin: Rifampicin-resistance does not always mean rifabutin-resistance, and the laboratory should be asked to test for it. It is possible to use only one drug within each drug class.

  9. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    Researchers have found that the far more common overdose risk with Suboxone occurs when an addict shoots up the drug intravenously in combination with a respiratory depressant, such as a benzodiazepine like Xanax. The Times article did not question the efficacy of Suboxone when used properly.