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The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts.
Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. [ 3 ] [ 4 ] [ 2 ] Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can ...
The same Hox protein can act as a repressor at one gene and an activator at another. The ability of Hox proteins to bind DNA is conferred by a part of the protein referred to as the homeodomain. The homeodomain is a 60-amino-acid-long DNA-binding domain (encoded by its corresponding 180-base-pair DNA sequence, the homeobox
"The fat and protein in the nuts help keep you full, so you don’t need to eat a lot of them to reap the weight-loss benefits," says Natalie Rizzo, a registered dietitian and TODAY.com nutrition ...
19. "Grool. I meant to say cool but then I started to say great." — Cady Heron. 20. "Don't have sex. Because you will get pregnant, and die. Don't have sex in the missionary position, don't have ...
Instead, Dr. Danda offers up these phrases: “Happy you’re home,” “Glad you’re back,” or “I’m happy to see your smiling face.” “Parents can also make observations about ...
Here are the best quotes from the cult-classic film "Mean Girls," based on usability. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 more ...
Andy Strickland in Record Mirror said, "Morrissey and Marr still can't quite get it together all the time, 'Never Had No One Ever' and 'Some Girls Are Bigger Than Others' bearing all the hallmarks of the familiar Smiths filler, where music and words hardly embrace," [5] while Nick Kent wrote, "'Vicar in a Tutu' and 'Some Girls Are Bigger Than ...