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  2. Ropeginterferon alfa-2b - Wikipedia

    en.wikipedia.org/wiki/Ropeginterferon_alfa-2b

    [3] [6] Ropeginterferon alfa-2b is the first medication approved by the US Food and Drug Administration (FDA) to treat polycythemia vera that people can take regardless of their treatment history, and the first interferon therapy specifically approved for polycythemia vera. [3] The FDA considers it to be a first-in-class medication. [7]

  3. Chlornaphazine - Wikipedia

    en.wikipedia.org/wiki/Chlornaphazine

    Chlornaphazine, a derivative of 2-naphthylamine, is a nitrogen mustard that was developed in the 1950s for the treatment of polycythemia and Hodgkin's disease. [1] However, a high incidence of bladder cancers in patients receiving treatment with chlornaphthazine led to use of the drug being discontinued.

  4. Polycythemia - Wikipedia

    en.wikipedia.org/wiki/Polycythemia

    Polycythemia vera (PCV) (a.k.a. polycythemia rubra vera (PRV)) occurs when excess red blood cells are produced as a result of an abnormality of the bone marrow. [3] Often, excess white blood cells and platelets are also produced. A hallmark of polycythemia vera is an elevated hematocrit, with Hct > 55% seen in 83% of cases. [20]

  5. Polycythemia vera - Wikipedia

    en.wikipedia.org/wiki/Polycythemia_vera

    In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [2] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.

  6. Hydroxycarbamide - Wikipedia

    en.wikipedia.org/wiki/Hydroxycarbamide

    Hydroxycarbamide, also known as hydroxyurea, is an antimetabolite medication used in sickle-cell disease, essential thrombocythemia, chronic myelogenous leukemia, polycythemia vera, and cervical cancer. [4] [5] In sickle-cell disease it increases fetal hemoglobin and decreases the number of attacks. [4] It is taken by mouth. [4]

  7. Bloodletting - Wikipedia

    en.wikipedia.org/wiki/Bloodletting

    Therapeutic phlebotomy refers to the drawing of a unit of blood in specific cases like hemochromatosis, polycythemia vera, porphyria cutanea tarda, etc., to reduce the number of red blood cells. [6] [7] The traditional medical practice of bloodletting is today considered to be a pseudoscience. [8]

  8. Blood substitute - Wikipedia

    en.wikipedia.org/wiki/Blood_substitute

    It aims to provide an alternative to blood transfusion, which is transferring blood or blood-based products from one person into another. Thus far, there are no well-accepted oxygen-carrying blood substitutes, which is the typical objective of a red blood cell transfusion; however, there are widely available non-blood volume expanders for cases ...

  9. Talk:Polycythemia - Wikipedia

    en.wikipedia.org/wiki/Talk:Polycythemia

    polycythemia ruba vera is secondary polycythemia and has an underlying cause such as sleep apnea copd or anything that causes a rise in epo and is treatable by treating the underlying cause. polycythemia vera known as primary polycythemia has no secondary causes that can be found your oxygen levels are normal and you epo is normal or low.

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