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Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject covers topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics and epigenetics on neuronal development, and the molecular basis for neuroplasticity and ...
One such protein pathway is the REST co-repressor complex pathway. There are also several non-coding RNAs that regulate neural function at the epigenetic level. These mechanisms, along with neural histone methylation , affect arrangement of synapses , neuroplasticity, and play a key role in learning and memory.
2354 14282 Ensembl ENSG00000125740 ENSMUSG00000003545 UniProt P53539 P13346 RefSeq (mRNA) NM_001114171 NM_006732 NM_008036 NM_001347586 RefSeq (protein) NP_001107643 NP_006723 NP_001334515 NP_032062 Location (UCSC) Chr 19: 45.47 – 45.48 Mb Chr 7: 19.04 – 19.04 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Protein fosB, also known as FosB and G0/G1 switch regulatory protein 3 ...
In neuroscience, synaptic plasticity is the ability of synapses to strengthen or weaken over time, in response to increases or decreases in their activity. [1] Since memories are postulated to be represented by vastly interconnected neural circuits in the brain , synaptic plasticity is one of the important neurochemical foundations of learning ...
Most often, the threshold potential is a membrane potential value between –50 and –55 mV, [1] but can vary based upon several factors. A neuron's resting membrane potential (–70 mV) can be altered to either increase or decrease likelihood of reaching threshold via sodium and potassium ions.
Neurotrophic factors also promote the initial growth and development of neurons in the central nervous system and peripheral nervous system, and they are capable of regrowing damaged neurons in test tubes and animal models. [1] [4] Some neurotrophic factors are also released by the target tissue in order to guide the growth of developing axons.
Long-term potentiation (LTP) is a persistent increase in synaptic strength following high-frequency stimulation of a chemical synapse. Studies of LTP are often carried out in slices of the hippocampus, an important organ for learning and memory. In such studies, electrical recordings are made from cells and plotted in a graph such as this one.
This particular field within neuroscience examines how neurochemicals influence the operation of neurons, synapses, and neural networks. Neurochemists analyze the biochemistry and molecular biology of organic compounds in the nervous system, and their roles in such neural processes including cortical plasticity, neurogenesis, and neural ...