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HPV types 6 and 11 are responsible for causing majority of genital warts whereas HPV types 16, 18, 31, 33, and 35 are also occasionally found. [5] It is spread through direct skin-to-skin contact, usually during oral , manual , vaginal , or anal sex with an infected partner.
Genital warts can be removed by freezing. [5] Nearly every sexually active individual is infected by HPV at some point in their lives. [4] HPV is the most common sexually transmitted infection (STI), globally. [5] High-risk HPVs cause about 5% of all cancers worldwide and about 37,300 cases of cancer in the United States each year. [10]
VP are not infectious and not due to HPV. [1] Diagnosis is by visualization. [1] The bumps are less yellow and more pinkish when compared to Fordyce spots. [2] They should not be mistaken for genital warts. [3] No treatment is required. [1] They are common in pregnancy. [1] Historically they were sometimes incorrectly called "microwarts". [3]
The highest-risk types are HPV 16 and 18; these are responsible for the vast majority of HPV-related cancers, including cancers of the cervix, vagina, vulva, penis, anus, and head and neck.
Gardasil 6 is an HPV vaccine aimed at preventing cervical cancers and genital warts. Gardasil is designed to prevent infection with HPV types 16, 18, 6, and 11. HPV types 16 and 18 currently cause about 70% of cervical cancer cases, [13] [14] and also cause some vulvar, vaginal, [11] penile and anal cancers. [12]
A squamous cell papilloma is a generally benign papilloma that arises from the stratified squamous epithelium of the skin, lip, oral cavity, tongue, pharynx, larynx, esophagus, cervix, vagina or anal canal.
HPV DNA can be found in up to 87% of vulvar intraepithelial neoplasia (VIN) and 29% of invasive vulvar cancers; HPV 16 is the most commonly detected subtype in VIN and vulvar cancer, followed by HPV 33 and HPV 18. [15] VIN is a superficial lesion of the skin that has not invaded the basement membrane—or a pre-cancer. [16]
When used without context, it frequently refers to infections (squamous cell papilloma) caused by human papillomavirus (HPV), such as warts. Human papillomavirus infection is a major cause of cervical cancer, vulvar cancer, vaginal cancer, penis cancer, anal cancer, and HPV-positive oropharyngeal cancers.
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