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  2. Runs of homozygosity - Wikipedia

    en.wikipedia.org/wiki/Runs_of_Homozygosity

    Runs of homozygosity (ROH) are contiguous lengths of homozygous genotypes that are present in an individual due to parents transmitting identical haplotypes to their offspring. [ 1 ] The potential of predicting or estimating individual autozygosity for a subpopulation is the proportion of the autosomal genome above a specified length, termed F ...

  3. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    Zygosity (the noun, zygote, is from the Greek zygotos "yoked," from zygon "yoke") (/ z aɪ ˈ ɡ ɒ s ɪ t i /) is the degree to which both copies of a chromosome or gene have the same genetic sequence.

  4. Major histocompatibility complex and sexual selection

    en.wikipedia.org/wiki/Major_histocompatibility...

    MHC-based sexual selection is known to involve olfactory mechanisms in such vertebrate taxa as fish, mice, humans, primates, birds, and reptiles. [1] At its simplest level, humans have long been acquainted with the sense of olfaction for its use in determining the pleasantness or the unpleasantness of one's resources, food, etc.

  5. Pedigree collapse - Wikipedia

    en.wikipedia.org/wiki/Pedigree_collapse

    Without pedigree collapse, a person's ancestor tree is a binary tree, formed by the person, the parents (2), the grandparents (4), great-grandparents (8), and so on.. However, the number of individuals in such a tree grows exponentially and will eventually become impossibl

  6. Loss of heterozygosity - Wikipedia

    en.wikipedia.org/wiki/Loss_of_heterozygosity

    This acquired homozygosity could lead to development of cancer if the individual inherited a non-functional allele of a tumor suppressor gene. In tumor cells copy-neutral LOH can be biologically equivalent to the second hit in the Knudson hypothesis. [ 3 ]

  7. Haplogroup K (mtDNA) - Wikipedia

    en.wikipedia.org/wiki/Haplogroup_K_(mtDNA)

    This high percentage points to a genetic bottleneck occurring around the years 800-1000 [23] under which K1a1b1a was particularly affected since K1a1b1a carriers' proportions of founder alleles and pathogenic variants were higher than in carriers of other haplogroups, and the K1a1b1a carriers had longer total lengths for runs of homozygosity ...

  8. ROH - Wikipedia

    en.wikipedia.org/wiki/Roh

    Runs of homozygosity, in DNA sequencing; Formula of a generic alcohol (substituent R, Oxygen, Hydrogen) Romansh language, ISO 639 language code roh; See also.

  9. Inbred strain - Wikipedia

    en.wikipedia.org/wiki/Inbred_strain

    Inbred strains (also called inbred lines, or rarely for animals linear animals) are individuals of a particular species which are nearly identical to each other in genotype due to long inbreeding.