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Surfactant therapy is the medical administration of pulmonary surfactant that is derived from outside of the body. Pulmonary surfactant is a soap-like chemical synthesized by type II alveolar pneumocytes and is of various lipids (80% phospholipids, 5-10% cholesterol, and ∼10% surfactant-associated proteins).
Pulmonary surfactant is used as a medication to treat and prevent respiratory distress syndrome in newborn babies. [ 1 ] Prevention is generally done in babies born at a gestational age of less than 32 weeks. [ 1 ]
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent [citation needed] (containing mucus and pus) bronchopulmonary secretions, [1] [2] administered by inhalation through a nebulizer [3] or with a stream of oxygen.
It is used to treat pulmonary alveolar proteinosis, in which excess lung surfactant proteins prevent the patient from breathing. [1] [2] Some sources consider it a variation of bronchoalveolar lavage. [3] WLL has been experimentally used for silicosis, [4] other forms of mineral inhalation, and accidental inhalation of radioactive dust. [5]
Poractant alfa is an extract of natural porcine lung surfactant. As with other surfactants, marked improvement on oxygenation may occur within minutes of the administration of poractant alfa. The new generic form of surfactant is Varasurf (Sheep Lung Surfactant) developed in PersisGen Co. and commercialized by ArnaGen Pharmad.
As of 2019, there is no evidence showing that treatments with exogenous surfactants, statins, beta-blockers or n-acetylcysteine decreases early mortality, late all-cause mortality, duration of mechanical ventilation, or number of ventilator-free days. [31]
A sex offender who police said tried to "financially and emotionally manipulate" his victims has been jailed for 25 years. Stephen Gallagher, of Normandy Avenue in Colchester, was found guilty by ...
Willardiine (correctly spelled with two successive i's) or (S)-1-(2-amino-2-carboxyethyl)pyrimidine-2,4-dione is a chemical compound that occurs naturally in the seeds of Mariosousa willardiana and Acacia sensu lato. [1]
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