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Calone, a derivative of 4-methylcatechol, is known in the fragrance industry as "watermelon ketone" for its distinctive odor. [3]The brand of low-temperature coke used as a smokeless fuel Coalite obtains homocatechol from ammoniacal liquor by solvent extraction, distillation and crystallisation.
The enzyme introduces a methyl group to the catecholamine, which is donated by S-adenosyl methionine (SAM). Any compound having a catechol structure, like catecholestrogens and catechol-containing flavonoids, are substrates of COMT. Levodopa, a precursor of catecholamines, is an important substrate of COMT.
Catechol (/ ˈ k æ t ɪ tʃ ɒ l / or / ˈ k æ t ɪ k ɒ l /), also known as pyrocatechol or 1,2-dihydroxybenzene, is an organic compound with the molecular formula C 6 H 4 (OH) 2. It is the ortho isomer of the three isomeric benzenediols .
There are three structural isomers: 1,2-dihydroxybenzene (the ortho isomer) is commonly known as catechol, 1,3-dihydroxybenzene (the meta isomer) is commonly known as resorcinol, and 1,4-dihydroxybenzene (the para isomer) is commonly known as hydroquinone. [1]
Catechol. A catecholamine (/ ˌ k æ t ə ˈ k oʊ l ə m iː n /; abbreviated CA) is a monoamine neurotransmitter, an organic compound that has a catechol (benzene with two hydroxyl side groups next to each other) and a side-chain amine. [1] Catechol can be either a free molecule or a substituent of a larger molecule, where it represents a 1,2 ...
It consists of 4 exons and is a 30 kDa protein. It shares many properties found among the other methyltransferases. It is closest in sequence to glycine-N-methyl transferase . It also shares many structural properties like the shape of the folding lip with catechol-O-methyl transferase (COMT), though it shares less sequence identity. Several ...
[medical citation needed] For maximum sympathomimetic activity, a drug must have: Amine group two carbons away from an aromatic group; A hydroxyl group at the chiral beta position in the R-configuration; Hydroxyl groups in the meta and para position of the aromatic ring to form a catechol which is essential for receptor binding
4-Methylethcathinone or 4-MEC is a chemical that bears a chemical resemblance to mephedrone. [3] Due to its similarity to mephedrone, it is thought to be a stimulant and entactogen drug of the phenethylamine , amphetamine , and cathinone chemical classes . [ 4 ]