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Depending on the dose, the drug can produce paradoxical effects, including CNS stimulation or depression. Most antihistamines exhibit some type of anticholinergic activity. Antihistamines act by competitively binding to H 1-receptor sites, thus blocking the binding of endogenous histamine. Antihistamines do not chemically inactivate or prevent ...
H 1-antihistamines are clinically used in the treatment of histamine-mediated allergic conditions. These indications may include: [4] Allergic rhinitis; Allergic conjunctivitis; Allergic dermatological conditions (contact dermatitis) Rhinorrhea (runny nose) Urticaria; Angioedema; Diarrhea; Pruritus (atopic dermatitis, insect bites)
Benadryl is a brand of various antihistamine medications used to stop allergies, whose content varies in different countries, but which includes some combination of diphenhydramine, acrivastine, and/or cetirizine. It is sold by Kenvue and is used to relieve allergy symptoms such as sneezing, itching, runny nose, rash, and hives. [1]
Dimetapp is an American brand of over-the-counter cold and allergy medicines that is manufactured by Foundation Consumer Brands. At one point, Dimetapp as a household word referred to a single combination preparation marketed to relieve symptoms of the common cold, containing brompheniramine (an antihistamine) and phenylephrine (decongestant replacing the formerly used pseudoephedrine, which ...
Decongestants are also used to reduce redness in the treatment of simple conjunctivitis. A 2016 Cochrane review found insufficient evidence to support the use of intranasal corticosteroids in the relief of common cold symptoms; [ 2 ] however, the review was based on three trials and the quality of the evidence was regarded as very low.
Additionally, if you have a persistent watery runny nose from one side of your nose, especially faucet-like drainage, this could be a sign of a spinal fluid leak and you should seek medical care ...
pentoxyfylline – xanthine derivative used in as an antiinflammatory drug and in the prevention of endotoxemia; pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID)
The number of receptors decreases, and when the administration of the drug is ceased, chronic congestion can occur; this is called rhinitis medicamentosa, commonly referred to as rebound congestion. Moreover, long-term overdosing can cause degenerative changes in nasal mucous membranes that pose another health problem.
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