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Lymphedema, also known as lymphoedema and lymphatic edema, is a condition of localized swelling caused by a compromised lymphatic system. [2] The lymphatic system functions as a critical portion of the body's immune system and returns interstitial fluid to the bloodstream.
Usually this is localized (for example, an infected spot on the scalp will cause lymph nodes in the neck on that same side to swell). However, when two or more lymph node groups are involved, it is called generalized lymphadenopathy. Usually this is in response to significant systemic disease and will subside once the person has recovered.
Size, where lymphadenopathy in adults is often defined as a short axis of one or more lymph nodes is greater than 10mm. [29] By extent: Localized lymphadenopathy: due to localized spot of infection; e.g., an infected spot on the scalp will cause lymph nodes in the neck on that same side to swell up
The term 'cervical' refers to the cervical lymph nodes in the neck; it is unrelated to the cervix. The alternative name scrofula comes from the medieval Latin scrōfula , diminutive of scrōfa , meaning brood sow , because swine were supposed to be subject to the complaint, [ citation needed ] or because the line of elevated lymph nodes was ...
Adult onset of Kawasaki disease is rare. [50] The presentation differs between adults and children: in particular, it seems that adults more often have cervical lymphadenopathy, hepatitis, and arthralgia. [32] [50] Some children, especially young infants, [51] have atypical presentations without the classic set of symptoms. [48]
Milroy's disease is also known as primary or hereditary lymphedema type 1A or early onset lymphedema. It is a very rare disease with only about 200 cases reported in the medical literature. Milroy's disease is an autosomal dominant condition caused by a mutation in the FLT4 gene which encodes the vascular endothelial growth factor receptor 3 ...
Lymphedema most commonly arises in the arms or legs, but can also occur in the chest wall, genitals, neck, and abdomen. [37] Secondary lymphedema usually results from the removal of lymph nodes during breast cancer surgery or from other damaging treatments such as radiation. It can also be caused by some parasitic infections.
Because of the prolonged survival, which was typically about 10 years in past decades, but which can extend to a normal life expectancy, the prevalence (number of people living with the disease) is much higher than the incidence (new diagnoses). [2] CLL is the most common type of leukemia in the UK, accounting for 38% of all leukemia cases.
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