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Areas of interest described in Isbell's published work include physical and psychological effects of individual substances (including potential for dependence and addiction), ways to mitigate withdrawal symptoms (e.g., methadone therapy), the development of reliable rating methods and questionnaires for subjective drug effects (the Addiction Research Center Inventory), [24] [25] cross-drug ...
The latter reflects physical dependence in which the body adapts to the drug, requiring more of it to achieve a certain effect (tolerance) [25] and eliciting drug-specific physical or mental symptoms if drug use is abruptly ceased (withdrawal). Physical dependence can happen with the chronic use of many drugs—including even appropriate ...
The experiments began some time in 1960 and lasted until March 1962, when other professors in the Harvard Center for Research in Personality raised concerns about the legitimacy and safety of the experiments in an internal meeting. [3] [4] [5] Leary and Alpert's experiments were part of their personal discovery and advocacy of psychedelics.
Knight and his colleagues first assessed other brief substance abuse screening tests. 1-3 They then developed a new brief screener known as “CRAFFT” that was shown to be valid, reliable, developmentally appropriate for adolescents, and practical for use in busy pediatric offices. 4,5 CRAFFT has since become the American Academy of Pediatrics’ recommended standard of care in its policy ...
In 1987, the DSM-IIIR category "psychoactive substance abuse", which includes former concepts of drug abuse is defined as "a maladaptive pattern of use indicated by...continued use despite knowledge of having a persistent or recurrent social, occupational, psychological or physical problem that is caused or exacerbated by the use (or by ...
Concord Prison. The Concord Prison Experiment, conducted from 1961 to 1963, was designed to evaluate whether the experiences produced by the psychoactive drug psilocybin, derived from psilocybin mushrooms, combined with psychotherapy, could inspire prisoners to leave their antisocial lifestyles behind once they were released.
The Spring Grove Experiments were adapted to study the effect of LSD and psychotherapy on patients including alcoholics, [2] [1] [3] heroin addicts, neurotics, and terminally-ill cancer patients. The research done was largely conducted by the members of the Research Department of Spring Grove State Hospital.
Emoto claimed that water was a "blueprint for our reality" and that emotional "energies" and "vibrations" could change its physical structure. [14] His water crystal experiments consisted of exposing water in glasses to various words, pictures, or music, then freezing it and examining the ice crystals' aesthetic properties with microscopic photography. [9]