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Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of acne vulgaris. [1] [2] It is a combination of adapalene, a retinoid; and benzoyl peroxide. [1] [2] It is available as a generic medication. [3]
Adapalene, sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. [6] Studies have found adapalene is as effective as other retinoids, while causing less irritation. [7]
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
Tazarotene, sold under the brand name Tazorac, among others, is a third-generation prescription topical retinoid. [2] [3] It is primarily used for the treatment of plaque psoriasis and acne. [4]
- I will use up to date articles/reviews regarding adapalene’s indications, off label uses, efficacy, and mechanism of action to expand the article. - I will restructure the article so the sections flow better and the article is easier to follow. By 3/8: Select one article and draft work plan.
The origins of Galderma date back to 1961 and the founding of the Owen dermatology company in Dallas, Texas, USA by M. Owen. [4]. In 1979, Hans Schaefer founded the International Center for Dermatological Research (CIRD) in Sophia Antipolis, with the support of the CEO of L'Oréal, François Dalle, who wanted to diversify his cosmetic research into the drug sector.
Dapsone, also known as 4,4'-sulfonyldianiline (SDA) or diaminodiphenyl sulfone (DDS), [3] is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. [4]
eBay Inc. v. MercExchange, L.L.C., 547 U.S. 388 (2006), is a case in which the Supreme Court of the United States unanimously determined that an injunction should not be automatically issued based on a finding of patent infringement, but also that an injunction should not be denied simply on the basis that the plaintiff does not practice the patented invention. [1]
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