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  2. Clostridioides difficile - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile

    Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [ 4 ] [ 5 ] It is known also as C. difficile , or C. diff ( / s iː d ɪ f / ), and is a Gram-positive species of spore -forming bacteria. [ 6 ]

  3. Clostridioides difficile infection - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    Clostridioides difficile infection [5] (CDI or C-diff), also known as Clostridium difficile infection, is a symptomatic infection due to the spore-forming bacterium Clostridioides difficile. [6] Symptoms include watery diarrhea, fever, nausea, and abdominal pain. [1] It makes up about 20% of cases of antibiotic-associated diarrhea. [1]

  4. Clostridioides difficile toxin A - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    Clostridioides difficile toxin A (TcdA) is a toxin produced by the bacteria Clostridioides difficile, formerly known as Clostridium difficile. [1] It is similar to Clostridioides difficile Toxin B . The toxins are the main virulence factors produced by the gram positive , anaerobic, [ 2 ] Clostridioides difficile bacteria.

  5. Clostridium - Wikipedia

    en.wikipedia.org/wiki/Clostridium

    Clostridium is a genus of anaerobic, Gram-positive bacteria.Species of Clostridium inhabit soils and the intestinal tracts of animals, including humans. [1] This genus includes several significant human pathogens, including the causative agents of botulism and tetanus.

  6. Opportunistic infection - Wikipedia

    en.wikipedia.org/wiki/Opportunistic_infection

    Clostridioides difficile (formerly known as Clostridium difficile) is a species of bacteria that is known to cause gastrointestinal infection and is typically associated with the hospital setting. [7] [8] Legionella pneumophila is a bacterium that causes Legionnaire's disease, a respiratory infection. [9] [10]

  7. Clostridioides - Wikipedia

    en.wikipedia.org/wiki/Clostridioides

    The genus Clostridioides was created to describe a few species formerly in the genus Clostridium which have been shown to be their own genetically distinct genus using 16S rRNA gene sequencing analysis. [1] However, both names are still in use and valid under the International Code of Nomenclature of Prokaryotes. [2]

  8. Clostridioides difficile toxin B - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    Bezlotoxumab is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infections. By x-ray crystallized structure of N-terminal of TcdB, the toxin is identified to consist of three domains: a glucosyltransferase domain (GTD), a cysteine protease and a combined repetitive oligopeptide (CROP) domain.

  9. Fecal microbiota transplant - Wikipedia

    en.wikipedia.org/wiki/Fecal_microbiota_transplant

    Scanning electron micrograph of Clostridioides difficile bacteria from a stool sample. Fecal microbiota transplant is approximately 85–90% effective in people with CDI for whom antibiotics have not worked or in whom the disease recurs following antibiotics.

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