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Phineas P. Gage (1823–1860) was an American railroad construction foreman remembered for his improbable: 19 survival of an accident in which a large iron rod was driven completely through his head, destroying much of his brain's left frontal lobe, and for that injury's reported effects on his personality and behavior over the remaining 12 years of his life—effects sufficiently ...
White matter fiber connections in DTI data are then drawn between these cortical regions and weighted by fractional anisotropy and strength of the connection. Such graphs have even been used to analyze the damage done to the famous traumatic brain injury patient Phineas Gage. [56]
Descartes' Error: Emotion, Reason, and the Human Brain is a 1994 book by neuroscientist António Damásio describing the physiology of rational thought and decision, and how the faculties could have evolved through Darwinian natural selection. [1]
Connectograms have been used to monitor the progression of neurological recovery of patients who suffered a traumatic brain injury (TBI). [12] They have also been applied to famous patient Phineas Gage, to estimate damage to his neural network (as well as the damage at the cortical level—the primary focus of earlier studies on Gage). [13]
The first case study on Phineas Gage's head injury is one of the most astonishing brain injuries in history. In 1848, Phineas Gage was paving way for a new railroad line when he encountered an accidental explosion of a tamping iron straight through his frontal lobe. Gage observed to be intellectually unaffected but exemplified post-injury ...
Phineas Gage, who sustained a severe frontal lobe injury in 1848, has been called a case of dysexecutive syndrome. Gage's psychological changes are almost always exaggerated – of the symptoms listed, the only ones Gage can be said to have exhibited are "anger and frustration", slight memory impairment, and "difficulty in planning". [21]
Damage to the ventromedial prefrontal cortex led Phineas Gage to act without any moral consideration. The most studied case of a brain lesion affecting the neuromoral network was that of Phineas Gage who suffered from damage to the ventromedial prefrontal cortex due to an accident. [ 28 ]
White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. [1] Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials , acting as a relay and coordinating communication between different brain ...