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Hepatitis B virus (HBV) is a partially double-stranded DNA virus, [1] a species of the genus Orthohepadnavirus and a member of the Hepadnaviridae family of viruses. [2] [3] This virus causes the disease hepatitis B. [4]
Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver; [1] [6] it is a type of viral hepatitis. [7] It can cause both acute and chronic infection . [ 1 ]
The virus first known to cause hepatitis was the yellow fever virus, a mosquito-borne flavivirus. Other viruses than can cause hepatitis include: Adenoviruses; Arenaviruses: Guanarito virus, Junín virus, Lassa fever virus, Lujo virus, Machupo virus, and Sabiá virus [28]
Hepadnaviruses, as their "hepa" name implies, infect liver cells and cause hepatitis. This is true not only of the human pathogen Hepatitis B Virus but also the hepadnaviruses that infect other organisms. The "adhesion" step of the dynamic phase—in which an exterior viral protein stably interacts with a host cell protein—determines cell ...
One general mechanism, increased DNA damage, is shared by some of the major liver diseases, including infection by hepatitis B virus or hepatitis C virus, heavy alcohol consumption, and obesity. [24] Viral infection by hepatitis B virus, or hepatitis C virus causes an increase of reactive oxygen species.
The pediatric hepatitis outbreak with no known cause may be due to long COVID, a new study finds. 700 cases of mystery hepatitis in kids have popped up globally.
Hepatitis B is the most common cause of viral hepatitis in the world with more than 240 million chronic carriers of the virus, 1 million of whom are in the United States. [ 31 ] [ 106 ] In approximately two-thirds of patients who develop acute hepatitis B infection, no identifiable exposure is evident. [ 17 ]
HBV is the most common one among those hepatitis viruses. It can cause chronic infection of liver in humans, which has become a global public health problem, since chronic hepatitis can cause cirrhosis or death from liver failure within certain times. And it is the major cause of HCC, contributing about 60-80% of the HCC cases around the world.
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