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The Clinical Opiate Withdrawal Scale (COWS) is a method used by registered practitioners to measure the severity of a patient's opioid withdrawal symptoms. This method consists of a series of 11 topics each comprising 4–5 common symptoms experienced by a patient undergoing opioid withdrawal. In each topic a rank is given depending on what the ...
The Journal of Psychoactive Drugs is a peer-reviewed medical journal on psychoactive drugs. It was established in 1967 by David E. Smith and is currently published five times per year by Taylor & Francis. It was previously titled Journal of Psychedelic Drugs until 1980.
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) [1] was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and pharmacology of such agents—in his mid-life and later, many through preparation in his home laboratory, and testing on himself. [2]
The system was developed for research purposes by the American biochemist Alexander Shulgin, and published with co-authors Ann Shulgin and Peyton Jacob, III, in a 1986 issue of the journal Methods and Findings in Experimental and Clinical Pharmacology. It was later described in the Shulgins' popular 1991 book PIHKAL: A Chemical Love Story. [1] [2]
The severity of symptoms can be assessed by validated withdrawal scales, such as the Clinical Opiate Withdrawal Scale (COWS). [15] There is no test to diagnose for morphine withdrawal. [7] However, a toxicology test using urine is conducted to determine if withdrawal symptoms are caused by other non-opioid drugs or a combination of both. [7]
Psychoactive drugs operate by temporarily affecting a person's neurochemistry, which in turn causes changes in a person's mood, cognition, perception and behavior. There are many ways in which psychoactive drugs can affect the brain. Each drug has a specific action on one or more neurotransmitter or neuroreceptor in the brain.
Substance-induced psychosis (commonly known as toxic psychosis or drug-induced psychosis) is a form of psychosis that is attributed to substance intoxication, withdrawal or recent consumption of psychoactive drugs. It is a psychosis that results from the effects of various substances, such as medicinal and nonmedicinal substances, legal and ...
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