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The melanin in the skin is produced by melanocytes, which are found in the basal layer of the epidermis. Although, in general, human beings possess a similar concentration of melanocytes in their skin, the melanocytes in some individuals and ethnic groups produce variable amounts of melanin.
Melanocytes are melanin-producing neural crest-derived [3] cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), [4] the inner ear, [5] vaginal epithelium, [6] meninges, [7] bones, [8] and heart found in many mammals and birds. [9] Melanin is a dark pigment primarily responsible ...
Micrograph of keratinocytes, basal cells and melanocytes in the epidermis Keratinocytes (stained green) in the skin of a mouse. Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [1]
Eumelanin is the dominant form of melanin found in human skin. Eumelanin protects tissues and DNA from the radiation damage of UV light. Melanin is produced in specialized cells called melanocytes, which are found at the lowest level of the epidermis. [57] Melanin is produced inside small membrane-bound packages called melanosomes. People with ...
The amount and distribution of melanin pigment in the epidermis is the main reason for variation in skin color in Homo sapiens. Melanin is found in the small melanosomes, particles formed in melanocytes from where they are transferred to the surrounding keratinocytes. The size, number, and arrangement of the melanosomes vary between racial ...
Melanin is a derivative of the amino acid tyrosine. Eumelanin is the dominant form of melanin found in human skin. Eumelanin protects tissues and DNA from radiation damage by UV light. Melanin is produced in specialized cells called melanocytes, which are found in the lowest level of the epidermis. [85]
One study compared the two shapes and recorded data that showed spherical particles located deep in the epidermis and dermis whereas ellipsoidal particles were mainly found in the stratum corneum and epidermal layers. [48] Nanorods are used in experiments because of their unique fluorescent properties but have shown mediocre penetration.
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 March 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...