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Patiromer was generally well tolerated in studies. Side effects that occurred in more than 2% of patients included in clinical trials were mainly gastro-intestinal problems such as constipation, diarrhea, nausea, and flatulence, and also hypomagnesemia (low levels of magnesium in the blood) in 5% of patients, because patiromer binds magnesium in the gut as well.
The drug is administered intravenously every 6 or 8 hr, typically over 3–30 min. It may also be administered by continuous infusion over four hours. Prolonged infusions are thought to maximize the time that serum concentrations are above the minimum inhibitory concentration (MIC) of the bacteria implicated in infection.
A package insert is a document included in the package of a medication that provides information about that drug and its use. For prescription medications, the insert is technical, providing information for medical professionals about how to prescribe the drug. Package inserts for prescription drugs often include a separate document called a ...
The largest discount will be for Merck's diabetes drug Januvia, which will be slashed to $113 for a 30-day supply, down from $527 as of 2023. The smallest discount is for blood cancer drug ...
DailyMed. DailyMed is a website operated by the U.S. National Library of Medicine (NLM) to publish up-to-date and accurate drug labels (also called a "package insert") to health care providers and the general public. The contents of DailyMed is provided and updated daily by the U.S. Food and Drug Administration (FDA).
August 12, 2024 at 8:33 AM. By Sneha S K and Sriparna Roy. (Reuters) -Ascendis Pharma said on Monday the U.S. Food & Drug Administration had approved its therapy to treat adult patients with a ...
In the United States, a boxed warning (sometimes " black box warning ", colloquially) is a type of warning that appears near the beginning of the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text [1] to emphasize it is of ...
MDMA “has been shown to be safe and effective in the right conditions,” says Sunil Aggarwal, M.D., Ph.D., a physician in Seattle, Washington, who had been hoping to soon prescribe the drug to ...