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It can be noted that memantine is an antagonist at α 7 nAChR, which may contribute to initial worsening of cognitive function during early memantine treatment. α 7 nAChR upregulates quickly in response to antagonism, which could explain the cognitive-enhancing effects of chronic memantine treatment.
Memantine/donepezil, sold under the brand name Namzaric among others, is a fixed dose combination medication used for the treatment of dementia of the Alzheimer's type. [1] It contains memantine , as the hydrochloride, a NMDA receptor antagonist ; and donepezil as the hydrochloride, an acetylcholinesterase inhibitor . [ 1 ]
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
That includes pushing patients towards generic drugs, which often cost less than the branded options once the patents expire. "In the US, over 90% of prescriptions are now generic. Those lower ...
Feb. 16—Maine health officials are revising the process for involuntarily committing mental health patients deemed at risk of harming themselves or others in light of a recent ruling by the ...
Following (or in lieu of) a hospital admission, support services available can include drop-in centers, visits from members of a community mental health team or Assertive Community Treatment team, supported employment [3] and patient-led support groups. Efforts to avoid repeated hospitalization include the obtaining of community treatment ...
Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not glia, observed in restricted brain regions of rats and certain other animal models exposed to large quantities of psychoactive drugs that inhibit the normal operation of the neuronal NMDA receptor.
Before he could answer, one of the officers interrupted: Incarcerated patients in the hospital weren’t allowed visitors; family members weren’t even allowed to know that their loved ones were ...