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  2. Splenomegaly - Wikipedia

    en.wikipedia.org/wiki/Splenomegaly

    Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...

  3. Spleen - Wikipedia

    en.wikipedia.org/wiki/Spleen

    Spleen length Women Men 155–159 cm: 6.4–12 cm: 160–164 cm: ... Normal range of spleen size for a given age in children This page was last edited on 30 ...

  4. Asplenia - Wikipedia

    en.wikipedia.org/wiki/Asplenia

    Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease

  5. Castell's sign - Wikipedia

    en.wikipedia.org/wiki/Castell's_sign

    The spleen of each patient was then quantitatively measured using chromium-labeled erythrocytes and radioisotope photoscan of the spleen. Castell showed those patients in the control group had a mean spleen size of 75 cm 2 with a range of 57 cm 2 to 75 cm 2 , while those who had a positive percussion sign had a mean spleen size of 93 cm 2 with ...

  6. Overwhelming post-splenectomy infection - Wikipedia

    en.wikipedia.org/wiki/Overwhelming_post...

    The risk is greatest for children and elderly (70+ years old), but it can happen at any age. Greater risk is associated with splenectomy for hematological conditions such as sickle cell anemia, thalassemia and tumours when compared to splenectomy due to trauma. [2] [4]

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  8. Wandering spleen - Wikipedia

    en.wikipedia.org/wiki/Wandering_spleen

    Wandering spleen is most commonly diagnosed in young children [3] as well as women between the ages of 20 and 40. [6] Even so, the disease is very rare and fewer than 500 occurrences of the disease have been reported as of 2005, [3] of which around 148 (including both children and adult cases) were documented to have been from between 1960 and ...

  9. Autosplenectomy - Wikipedia

    en.wikipedia.org/wiki/Autosplenectomy

    The spleen is an important immunological organ that acts as a filter for red blood cells, triggers phagocytosis of invaders, and mounts an immunological response when necessary. [2] Lack of a spleen, called asplenia, can occur by autosplenectomy or the surgical counterpart, splenectomy. Asplenia can increase susceptibility to infection. [3]