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A thymoma is a tumor originating from the epithelial cells of the thymus that is considered a rare neoplasm. [1] Thymomas are frequently associated with neuromuscular disorders such as myasthenia gravis; [2] thymoma is found in 20% of patients with myasthenia gravis. [3] Once diagnosed, thymomas may be removed surgically.
This process continues into old age, where whether with a microscope or with the human eye, the thymus may be difficult to detect, [4] although typically weighs 5–15 grams. [3] Additionally, there is an increasing body of evidence showing that age-related thymic involution is found in most, if not all, vertebrate species with a thymus ...
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Histologic specimen being placed on the stage of an optical microscope Human lung tissue stained with hematoxylin and eosin as seen under a microscope. Histology, [help 1] also known as microscopic anatomy or microanatomy, [1] is the branch of biology that studies the microscopic anatomy of biological tissues.
Gross anatomy (also called topographical anatomy, regional anatomy, or anthropotomy) is the study of anatomical structures that can be seen by unaided vision. Microscopic anatomy is the study of minute anatomical structures assisted with microscopes, and includes histology (the study of the organization of tissues), and cytology (the study of ...
Tonofibrils seen under electron microscopy can differentiate thymoma from other tumors such as carcinoid, Hodgkin's, and seminoma. Patients are usually asymptomatic but can present with myasthenia gravis-related symptoms, substernal pain, dyspnea, or cough. Invasive tumors can produce compression effects such as superior vena cava syndrome.
The resolution of a microscope is defined as the minimum separation needed between two objects under examination in order for the microscope to discern them as separate objects. This minimum distance is labelled δ. If two objects are separated by a distance shorter than δ, then they will appear as a single object in the microscope.
Compared to thymoma, the cells of thymic carcinoma behave aggressively; they are fast growing and have a higher likelihood of systemic spread. [ 4 ] The World Health Organization separates thymoma into categories from type A to C based on histology, with type C thymoma representing the equivalent of thymic carcinoma. [ 3 ]