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The craniofacial complex begins its progress in the fourth week of development, and results from neural crest cells migrating to form and fuse the facial primordia. [9] [10] Failures or deviations in this process result in craniofacial clefts, either CL or CP. [6] The range of variation in phenotype aligns with ancestry.
A cleft lip contains an opening in the upper lip that may extend into the nose. [1] The opening may be on one side, both sides, or in the middle. [1] A cleft palate occurs when the palate (the roof of the mouth) contains an opening into the nose. [1] The term orofacial cleft refers to either condition
A bifid nose (also known as cleft nose) is an uncommon congenital malformation which is characterized by the presence of a cleft between the two nostrils of the nose. [1] It is the result of a disturbance during embryological nose development. [2] It is part of the Tessier classification for craniofacial clefts. [3]
Cleft palate does not have laterality in the same sense that the cleft lip does. Rather, there are certain morphologic forms of cleft palate (described succinctly by the Veau classification, as explained in detail below). An isolated cleft of the palate (whether Veau-I soft palate only or Veau-II hard and soft palate) is a "midline" cleft.
The cleft associated with macrostomia is associated with improper or failed fusion of the mandibular and maxillary processes during embryonic development. [3] This can lead to a variety of abnormalities involving skin , subcutaneous tissue , facial muscles, and the mucous membrane . [ 5 ]
In 2002 and 2003, two living male infants with partial diprosopus were described in the medical literature in separate case reports. [ 17 ] [ 18 ] One infant was born with duplication of the nose and the cerebral frontal lobes, two widely spaced eyes, a small, underdeveloped central eye socket, and a large, asymmetric mouth.
Oral and maxillofacial surgery is a surgical specialty focusing on reconstructive surgery of the face, facial trauma surgery, the mouth, head and neck, and jaws, as well as facial plastic surgery including cleft lip and cleft palate surgery.
Malpuech facial clefting syndrome, also called Malpuech syndrome or Gypsy type facial clefting syndrome, [1] is a rare congenital syndrome.It is characterized by facial clefting (any type of cleft in the bones and tissues of the face, including a cleft lip and palate), a caudal appendage (a "human tail"), [2] [3] growth deficiency, intellectual and developmental disability, and abnormalities ...