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  2. Dengue Fever - National Institute of Allergy and Infectious...

    www.niaid.nih.gov/diseases-conditions/dengue-fever

    Dengue Fever. Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. This disease used to be called "break-bone" fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking. Health experts have known about dengue fever for more than 200 years.

  3. Dengue Fever Diagnosis | NIAID: National Institute of Allergy and...

    www.niaid.nih.gov/diseases-conditions/dengue-diagnosis

    Dengue Fever Diagnosis. NIAID-supported scientists are working to understand the pathology of dengue disease and to develop cost-effective, sensitive, and specific diagnostic tests for use in dengue-endemic countries. The goal of these tests is to provide early detection of the disease, distinguish between the different viral dengue, and ...

  4. Dengue Fever Prevention | NIAID: National Institute of Allergy...

    www.niaid.nih.gov/diseases-conditions/dengue-prevention

    Dengue Fever Prevention. NIAID researchers are actively engaged in the search for an effective vaccine against dengue fever. The vaccine approach that is currently been evaluated at NIAID for efficacy against dengue animal models and human trials is a weakened recombinant version (live-attenuated) of the dengue virus.

  5. New Tool Identifies Aedes Mosquito Exposure in People

    www.niaid.nih.gov/news-events/new-tool-identifies-aedes-mosquito-exposure-people

    The disease symptoms include fever, head and body aches, nausea and rash, and severe cases of dengue can be fatal. Each year, between 100 and 400 million people develop the disease, resulting in approximately 40,000 deaths. In places where dengue is common, it is often a major cause of illness.

  6. Dengue Fever Treatment | NIAID: National Institute of Allergy and...

    www.niaid.nih.gov/diseases-conditions/dengue-treatment

    Dengue Fever Treatment. NIAID-supported investigators are pursuing several approaches to treat dengue infection. Some scientists are working to identify cellular and viral proteins to use as targets for drug intervention. In other studies, researchers are generating and evaluating neutralizing monoclonal antibodies and small molecule drugs in ...

  7. Dengue Fever Biology & Transmission | NIAID: National Institute...

    www.niaid.nih.gov/diseases-conditions/dengue-biology-and-transmission

    New research findings are shedding light on the mechanisms of dengue infection, such as how the virus enters the cells and how the human immune system responds to dengue infection. Other NIAID projects are identifying the human and viral factors that determine and contribute to the severity and transmissibility of this disease.

  8. STAT3 Dominant-Negative Disease Symptoms & Diagnosis

    www.niaid.nih.gov/diseases-conditions/stat3dn-symptoms-diagnosis

    Signs and Symptoms. People with STAT3 dominant-negative disease (STAT3DN) have very high levels of IgE and may have recurrent infections of the skin and lungs. These infections are often caused by the bacterium Staphylococcus aureus but also may be caused by other bacteria and fungi. Patients also tend to have recurrent bone fractures ...

  9. NIAID Raises Awareness to Malaria-like Diseases in W. Africa

    www.niaid.nih.gov/news-events/arbovirus-blog

    Unlike malaria, however, where most cases are found in children under age 14, residents over age 50 were most likely to have been exposed to dengue, Zika or chikungunya viruses. “Despite the high exposure risk to dengue virus in southern Mali, dengue fever cases have rarely been reported,” the researchers write.

  10. Dengue Vaccine Research Study - National Institute of Allergy and...

    www.niaid.nih.gov/clinical-trials/dengue-vaccine-research-study

    Dengue fever (also called dengue hemorrhagic fever) is a mosquito-borne illness that occurs in tropical and subtropical areas of the world. A severe case of dengue fever can cause serious bleeding, a sudden drop in blood pressure, or death. By taking part in our research study, you can help us make better dengue vaccines that may be used to ...

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    www.niaid.nih.gov/node/7937?404message&requested_url=/topics/denguefever/pages/...

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