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Substrate reduction therapy is FDA approved and there is at least one treatment available on the market. [10] Gene therapy aims to replace a missing protein in the body through the use of vectors, usually viral vectors. [11] In gene therapy, a gene encoding for a certain protein is inserted into a vector. [11]
Sonalleve MR-HIFU is a medical system developed by Philips Healthcare for the treatment of uterine fibroids without surgery. The system uses non-invasive high-intensity focused ultrasound (HIFU) guided by magnetic resonance (MR), hence the acronym MR-HIFU. The procedure involves volumetric heating of fibroids with real-time feedback. [1]
Uterine fibroids, also known as uterine leiomyomas, fibromyoma or fibroids, are benign smooth muscle tumors of the uterus, part of the female reproductive system. [1] Most people [note 1] with fibroids have no symptoms while others may have painful or heavy periods. [1] If large enough, they may push on the bladder, causing a frequent need to ...
The code encompasses the Sonata ® Procedure, an innovative, incision-free treatment for symptomatic uterine fibroids that leverages Gynesonics’ proprietary Radiofrequency (RF) energy technology. Uterine fibroids affect up to 80% of women by the age of 50 and can cause debilitating symptoms, including heavy menstrual bleeding, pelvic pain ...
GDEPT is a suicide gene therapy in which the enzyme required for prodrug conversion is produced within the target cell, using a gene delivered to it by gene therapy. When an adequate differential exists between the targeted cell and endogenous tissue, non-toxic prodrug is administered and is subsequently converted into its toxic form within the ...
Wobenzym, a combination of proteolytic enzymes and the antioxidant rutin, works systemically by targeting various tissues and organs in the body.Wobenzym is targeted at modulating the immune response to restore a healthy balance between anti-inflammatory and pro-inflammatory cytokines. [1]
Myomectomy, sometimes also called fibroidectomy, refers to the surgical removal of uterine leiomyomas, also known as fibroids. In contrast to a hysterectomy, the uterus remains preserved and the woman retains her reproductive potential. It still may impact hormonal regulation and the menstrual cycle. [1]
It is metabolized primarily by peptidases and not by cytochrome P450 enzymes. [2] The elimination half-life of nafarelin is 2.5 to 3.0 hours by intranasal administration, whereas the half-life of nafarelin and its metabolites by subcutaneous injection is 85.5 hours. [2] Nafarelin is eliminated 44 to 55% in urine and 18.5 to 44.2% in feces. [2]
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