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In clinical trials, the most common adverse events which occurred at a rate ≥5% and ≥1.5 times placebo included paraesthesia (tingling in fingers/toes), dizziness, altered taste, insomnia, constipation, and dry mouth.
Vivus also developed an obesity drug, Qnexa (now called Qsymia), a combination of phentermine and topiramate, two existing weight-loss drugs. [4] On July 17, 2012, The U.S. Food and Drug Administration approved Qsymia ( phentermine and topiramate extended-release ), made by Vivus, as an addition to a reduced-calorie diet and exercise for ...
In the U.S., the Emergency Medical Treatment and Active Labor Act requires that hospitals treat all patients in need of emergency medical care without considering patients' ability to pay for service. [27] This government mandated care places a cost burden on medical providers, as critically ill patients lacking financial resources must be treated.
Journal of Cardiothoracic Surgery. 7: 55. doi: 10.1186/1749-8090-7-55. PMC 3410786. PMID 22697396. Delaney E, Rosinski D, Ellis H, Samolyk KA, Riley JB (June 2010). "An in-vitro comparison between Hemobag and non-Hemobag ultrafiltration methods of salvaging circuit blood following cardiopulmonary bypass". The Journal of Extra-corporeal Technology.
[27] In January 2013, at its final conference, ECHOUTCOME released preliminary results of its study which surveyed 1361 people "from academia" in Belgium, France, Italy and the UK. [ 27 ] [ 28 ] [ 29 ] The researchers asked the subjects to respond to 14 questions concerning their preferences for various health states and durations of those ...
During the early 1960s, American heart surgeon Denton Cooley successfully performed numerous bloodless open-heart surgeries on Jehovah's Witness patients. Fifteen years later, he and his associate published a report of more than 500 cardiac surgeries in this population, documenting that cardiac surgery could be safely performed without blood transfusion.
A study based on extrapolation from existing data sources estimated that 4.2 million people die within 30 days of surgery every year, with half of these deaths occurring in low- and middle-income countries. [2] Perioperative mortality figures can be published in league tables that compare the quality of hospitals. Critics of this system point ...
Emergency bypass surgery for the treatment of an acute myocardial infarction (MI) is less common than PCI or thrombolysis. From 1995 to 2004, the percentage of people with cardiogenic shock treated with primary PCI rose from 27.4% to 54.4%, while the increase in coronary artery bypass graft surgery (CABG) was only from 2.1% to 3.2%. [ 34 ]