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At exit 89, NC 8 joins the freeway and the road turns from northeast to due north. The next interchange is exit 97 (Old US 52) which provides access to both Welcome and the community of Midway. After exit 100 (Hickory Tree Road), I-285 enters the city of Winston-Salem. Exit 103 is for South Main Street, and exit 105 is for Clemmonsville Road.
Major intersections are NC 150, NC 66, NC 67, US 158 and US 52 between Greensboro and Winston-Salem. After Winston-Salem, it intersects I-40 once again but continues westerly passing through Lewisville, Yadkinville, Wilkesboro and Boone. Major highway junctions between Winston-Salem and Boone are US 601, I-77, NC 16, Blue Ridge Parkway, US 221 ...
The Salem Parkway is an 18.5-mile-long (29.8 km) freeway in the U.S. state of North Carolina, serving the city of Winston-Salem and the town of Kernersville.It is signed as U.S. Route 421 (US 421) for its entire length, though it is also concurrent with US 158 in downtown Winston-Salem and North Carolina Highway 150 (NC 150) between Winston-Salem and Kernersville.
In the future, as the freeway is upgraded, the I-285 designation will be extended north through Winston-Salem to meet the interchange with the Winston-Salem Northern Beltway. North of that point, I-74 will leave the beltway to join US 52 and the two will remain cosigned until reaching the current short segment of I-74 located south of Mount Airy.
The Winston-Salem Northern Beltway is a partially completed freeway loop around the city of Winston-Salem in North Carolina.The western section has been designated as North Carolina Highway 452 (NC 452), which will become I-274 when completed, and the eastern section of the beltway will is designated as North Carolina Highway 74 (NC 74), which will become part of I-74 when completed.
U.S. Highway 29 (US 29) is a United States Numbered Highway that runs for 168.7 miles (271.5 km) from the South Carolina state line, near Blacksburg, to the commonwealth of Virginia, near Danville. It is signed with north–south cardinal directions but is actually a northeast and southwest diagonal highway throughout the state.
North Carolina Highway 897 (NC 897) was an original state highway that traversed from NC 60/NC 65, in Winston-Salem, to SR 33 at the Virginia state line. Going north on Liberty Street, from 4th Street, in Winston-Salem, it went at a northeasterly route along Old Walkertown Road and Pine Hall Road to Pine Hall .
North Carolina Highway 109 (NC 109) is a north–south state highway in North Carolina.It primarily connects small towns in the central Piedmont region of the state. The 117-mile (188 km) route is a two-lane road for most of its length, but the segment between Winston-Salem and Thomasville is being upgraded to a divided 4-lane highway, as it is a major route between the two cities.