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Samoyeds can be affected by basement membrane disease of the kidneys. It is inherited through the X chromosome and is therefore more severe in affected male dogs. Findings in male dogs include the presence of protein and glucose in the urine and the inability to concentrate urine, and progression to kidney failure by the age of 9 months and death by 16 months. [3]
The antifreeze itself is not toxic, but is metabolized via the liver to the toxins glycolate and oxalate, which cause intoxication and vomiting, metabolic acidosis, and finally acute kidney failure leading to seizures and death. By the time clinical signs are observed, the kidneys are usually too damaged for the dog to survive, so acting ...
Cats can tolerate transplantation from unrelated cats, but must be supported with immunosuppressive drugs for the rest of their lives. When the transplanted kidney is implanted in the recipient the original kidneys are usually left in place. [1] There are currently ten centers in the world that offer kidney transplants for cats. Most are in the US.
Alabama rot, Greenetrack disease, or cutaneous and renal glomerular vasculopathy (CRGV) [1] is an often fatal condition in dogs. It was first identified in the US in the 1980s in greyhounds. [2] [3] The high number of affected dogs at the Greenetrack Racing Park, Alabama, led to the initial pseudonyms of Greenetrack Disease and Alabama Rot. [4]
It is a rare disease in dogs, with cats seven to ten times more likely to be infected. The disease in dogs can affect the lungs and skin, but more commonly the eye and central nervous system. [20] Ringworm is a fungal skin disease that in dogs is caused by Microsporum canis (70%), Microsporum gypseum (20%), and Trichophyton mentagrophytes (10% ...
NSAIDs caused no adverse effects on renal function in healthy dogs subjected to anesthesia. [11] [12] [13] Most healthy kidneys contain enough physiologic reserve to compensate for this NSAID-induced decrease in blood flow. However, those subjected to additional injury from phenacetin or paracetamol may progress to analgesic nephropathy ...
The reason some dogs develop kidney failure following ingestion of grapes and raisins is not known. [3] Types of grapes involved include both seedless and seeded, store-bought and homegrown, and grape pressings from wineries. [4] A mycotoxin is suspected to be involved, but none has been found in grapes or raisins ingested by affected dogs. [5]
Severe cases will develop bleeding disorders, which can cause hematomas to form in the mouth. [1] Death can occur secondary to this or the liver disease. However, most dogs recover after a brief illness, although chronic corneal edema and kidney lesions may persist. [3]