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Trazodone, sold under many brand names, [1] is an antidepressant medication [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
Anticonvulsant medications, such as gabapentin and pregabalin, may help to treat symptoms of certain anxiety disorders, such as generalized anxiety disorder and social anxiety disorder.
[6] [7] [8] They can completely block or reduce the effects of hallucinogens [6] or they can simply provide anxiety relief and sedation. [3] Examples of trip killers, in the case of serotonergic psychedelics , include serotonin receptor antagonists , like antipsychotics and certain antidepressants , and benzodiazepines .
Rare (<0.1%) adverse effects include: Urinary retention; Prolonged QT interval; Torsades de Pointes; Ataxia; Breast enlargement or engorgement; Lactation; Cardiospasm
GAD is a common disorder in which the central feature is excessively worrying about numerous events. Key symptoms include excessive anxiety about events and issues going on around them and difficulty controlling worrisome thoughts that persists for at least 6 months. Antidepressants provide a modest to moderate reduction in anxiety in GAD. [46]
Miindfulness-based stress reduction may be as effective as escitalopram (Lexapro — an SSRI commonly used to treat depression and anxiety), in relieving anxiety symptoms, a new study has found.
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