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Soman (or GD, EA 1210, Zoman, PFMP, A-255, systematic name: O-pinacolyl methylphosphonofluoridate) [1] is an extremely toxic chemical substance. It is a nerve agent , interfering with normal functioning of the mammalian nervous system by inhibiting the enzyme cholinesterase .
The symptoms of poisoning vary depending on substance, the quantity a dog has consumed, the breed and size of the mammal.A common list of symptoms are digestion problems, such as vomiting, diarrhea, or blood in stool; bruising and bleeding gums, nose, or inside the ear canal; behavioral changes, such as lethargy, hyperactivity, and seizures; unusual items found in the dog's stool.
White dog shaker syndrome causes full body tremors in small, white dog breeds. It is most common in West Highland White Terriers, Maltese, Bichons, and Poodles. [6] Wobbler disease (cervical instability) is a condition of the cervical vertebrae that causes an unsteady gait and weakness in dogs.
Skin conditions in dogs are very common, so it's important to recognize the symptoms and understand the factors that cause them. Dr. Rebecca MacMillan, a vet with over 15 years of experience, says ...
The health effects associated with organophosphate poisoning are a result of excess acetylcholine (ACh) present at different nerve synapses and neuromuscular junctions across the body. Specifically, acetylcholinesterase (AChE), the enzyme that normally and constantly breaks down acetylcholine, is inhibited by the organophosphate substance.
Vestibular disease may have many causes. Elderly dogs are susceptible to an idiopathic (meaning due to unknown causes) form of vestibular disease commonly called "old dog vestibular disease" or idiopathic peripheral vestibular disease. The signs may improve rapidly or take a few days.
Additionally, systemic aluminium levels are known to increase with age, and have been shown to correlate with Alzheimer's disease, implicating it as a neurotoxic causative compound of the disease. [72] Despite its known toxicity in its ionic form, studies are divided on the potential toxicity of using aluminium in packaging and cooking appliances.
Poisoning by a nerve agent leads to constriction of pupils, profuse salivation, convulsions, and involuntary urination and defecation, with the first symptoms appearing in seconds after exposure. Death by asphyxiation or cardiac arrest may follow in minutes due to the loss of the body's control over respiratory and other muscles.