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[1] [2] [3] Polyphenols include phenolic acids, flavonoids, tannic acid, and ellagitannin, some of which have been used historically as dyes and for tanning garments. Curcumin , a bright yellow component of turmeric ( Curcuma longa ), is a well-studied polyphenol.
Phenolic acids can be found in many plant species. Their content in dried fruits can be high.. Natural phenols in horse grams (Macrotyloma uniflorum) are mostly phenolic acids, namely 3,4-dihydroxy benzoic, p-hydroxy benzoic, vanillic, caffeic, p-coumaric, ferulic, syringic, and sinapinic acids.
It is difficult to evaluate the physiological effects of specific natural phenolic antioxidants, since such a large number of individual compounds may occur even in a single food and their fate in vivo cannot be measured. [1] [6] [8] Other more detailed chemical research has elucidated the difficulty of isolating individual phenolics.
Phenol (also known as carbolic acid, phenolic acid, or benzenol) is an aromatic organic compound with the molecular formula C 6 H 5 OH. [5] It is a white crystalline solid that is volatile . The molecule consists of a phenyl group ( −C 6 H 5 ) bonded to a hydroxy group ( −OH ).
UV visible spectrum of protocatechuic acid. Protocatechuic acid (PCA) is a dihydroxybenzoic acid, a type of phenolic acid. It is a major metabolite of antioxidant polyphenols found in green tea. It has mixed effects on normal and cancer cells in in vitro and in vivo studies. [4] It is produced commercially from vanillin. [5]
Aristolochic acid (contained in herbs in the genus Aristolochia e.g. Aristolochia serpentaria (Virginia snakeroot), Aristolochia reticulata (Texas snakeroot) and in Chinese herbs such as Aristolochia fangchi and Aristolochia manshuriensis [7] (banned in China and withdrawn from Chinese Pharmacopoea 2005; Stephania tetrandra and Magnolia ...
[23] [24] The aromatic amino acid phenylalanine, synthesized in the shikimic acid pathway, is the common precursor of phenol containing amino acids and phenolic compounds. In plants, the phenolic units are esterified or methylated and are submitted to conjugation , which means that the natural phenols are mostly found in the glycoside form ...
Phytochemicals are generally regarded as research compounds rather than essential nutrients because proof of their possible health effects has not been established yet. [4] [5] Phytochemicals under research can be classified into major categories, such as carotenoids [6] and polyphenols, which include phenolic acids, flavonoids, stilbenes or ...