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Such a quadruplex is described as tetramolecular, reflecting the requirement of four separate strands. The term G4 DNA was originally reserved for these tetramolecular structures that might play a role in meiosis. [5] However, as currently used in molecular biology, the term G4 can mean G-quadruplexes of any molecularity.
This DNAzyme cleaves complementary RNAs efficiently in a sequence specific manner between an unpaired purine and a paired pyrimidine. DNAzymes targeting AU or GU vs. GC or AC are more effective. Furthermore, the RNA cleavage rates have been shown to increase after the introduction of intercalators or the substitution of deoxyguanine with ...
A combination of DNAzyme and nanozyme was reported. [204] A peroxidase-like photoexcited Ru single-atom nanozyme was reported. [205] A probiotic nanozyme hydrogel for Candida vaginitis therapy was developed. [206] A method to determine the maximum velocity of a peroxidase-like nanozyme was proposed. [207]
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Incubation buffer conditions are altered based on the intended target and desired function of the selected aptamer. For example, in the case of negatively charged small molecules and proteins, high salt buffers are used for charge screening to allow nucleotides to approach the target and increase the chance of a specific binding event. [3]
A type of bacteria dubbed “Conan the Bacterium” can withstand radiation thousands of times stronger than what can kill a human. Now, scientists have figured out why.
As the year of 2024 wraps up, here's a list of travel trends in America that consumed folks on social media, including "gate lice," "seat squatters" and "sleep divorce."
New research links omega-6 fatty acids, commonly found in seed oils, and colon cancer growth. But there’s more to the story—and study if you read it carefully.